The transporter associated with antigen processing (TAP) is an ATP-binding cassette (ABC)
transporter essential to cellular immunity against viral infection. Some persistent viruses …

TAP1 and TAP2 genes encode heterodimeric molecule involved in endogenous antigen
processing. The present study was undertaken to find out the possible association between …

Hepatitis C virus (HCV) is the leading cause of liver fibrosis and hepatocellular carcinoma
(HCC). At present, there is no predictive biomarker for the patients at high risk of developing …

As a centerpiece of antigen processing, the ATP-binding cassette transporter associated
with antigen processing (TAP) became a main target for viral immune evasion. The …

Background: The hepatitis C virus (HCV) is a leading cause of liver disease and the
consequent complications of cirrhosis. However, there is no precise biomarker to predict the …

During pregnancy, the maternal immune system protects the allogeneic foetus from
rejection. At the same time the mother maintains immunity defences against potential …

The proteasome is a multicatalytic enzyme expressed in all eukaryotic cells and responsible
for the degradation of polyubiquitinated proteins. Thereby, the proteasome regulates protein …

Multiple sclerosis (MS) is a complex chronic immune-mediated disease of the central
nervous system, affecting approximately 1 in 1000 individuals in Europe and the US866 …

Рак молочной железы (РМЖ) в течение последних десятилетий является самым
распространенным онкологическим заболеванием среди женщин практически всех …

The HLA system is the most polymorphic genetic system described in humans. It consists of
several closely linked loci encoding cell surface glycoproteins whose best known function is …