Obesity and cardiovascular disease: friend or foe?

SH Kim, JP Després, KK Koh - European heart journal, 2016 - academic.oup.com
Obesity is currently one of the greatest public health issues worldwide. However, despite its
known deleterious effects on the cardiovascular system and its association with numerous …

Dietary regulation of adiponectin by direct and indirect lipid activators of nuclear hormone receptors

R Rühl, JF Landrier - Molecular nutrition & food research, 2016 - Wiley Online Library
Adiponectin is an adipokine mainly secreted by adipocytes that presents antidiabetic, anti‐
inflammatory, and antiatherogenic functions. Therefore, modulation of adiponectin …

Impact of 3-amino-1, 2, 4-triazole (3-AT)-derived increase in hydrogen peroxide levels on inflammation and metabolism in human differentiated adipocytes

FJ Ruiz-Ojeda, C Gomez-Llorente, CM Aguilera, A Gil… - PLoS …, 2016 - journals.plos.org
Obesity is characterized by an excessive accumulation of fat in adipose tissue, which is
associated with oxidative stress and chronic inflammation. Excessive H2O2 levels are …

Protein restriction during the last third of pregnancy malprograms the neuroendocrine axes to induce metabolic syndrome in adult male rat offspring

JC de Oliveira, RM Gomes, RA Miranda… - …, 2016 - academic.oup.com
Metabolic malprogramming has been associated with low birth weight; however, the
interplay between insulin secretion disruption and adrenal function upon lipid metabolism is …

Weight and weight change and risk of acute myocardial infarction and heart failure–the HUNT Study

I Janszky, P Romundstad, LE Laugsand… - Journal of internal …, 2016 - Wiley Online Library
Objectives To delineate the association of weight with cardiovascular health throughout
adulthood. Methods We conducted a population‐based prospective cohort study of 26 097 …

Swimming training attenuates the morphological reorganization of the myocardium and local inflammation in the left ventricle of growing rats with untreated …

E da Silva, AJ Natali, MF da Silva… - … -Research and Practice, 2016 - Elsevier
Diabetic cardiomyopathy is associated with cardiac remodeling, myocardial dysfunction, low-
grade inflammation, and reduced cardiac adiponectin in patients with type 1 diabetes …

[HTML][HTML] Globular adiponectin inhibits the apoptosis of mesenchymal stem cells induced by hypoxia and serum deprivation via the AdipoR1-mediated pathway

XQ Tian, YJ Yang, Q Li, PS Huang, XD Li… - Cellular Physiology and …, 2016 - karger.com
Background/Aims: Poor viability of transplanted mesenchymal stem cells (MSCs) within the
ischemic heart limits their therapeutic potential for cardiac repair. Globular adiponectin …

Rosuvastatin dose-dependently improves flow-mediated dilation, but reduces adiponectin levels and insulin sensitivity in hypercholesterolemic patients

KK Koh, PC Oh, I Sakuma, Y Lee, SH Han… - International Journal of …, 2016 - Elsevier
Background Genetic analysis from patients participated in the randomized trials reported
that the increased risk of type 2 diabetes noted with statins is at least partially explained by …

[HTML][HTML] Better prognosis in overweight/obese coronary heart disease patients with high plasma levels of leptin

LAV Simiti, I Todor, MA Stoia, CM Goidescu… - Clujul …, 2016 - ncbi.nlm.nih.gov
Methods Plasma levels of leptin in fifty nine consecutive patients (29 men and 30 women)
with CHD hospitalized in the County Emergency Clinical Hospital of Cluj-Napoca were …

Impact of statin therapy on plasma leptin concentrations: a systematic review and meta‐analysis of randomized placebo‐controlled trials

A Sahebkar, R Giua, C Pedone - British Journal of Clinical …, 2016 - Wiley Online Library
Objectives The effects of statins on insulin sensitivity, metabolic homeostasis and adipokines
in humans are controversial. Several studies have investigated the impact of statin therapy …