Discovery of bioactive molecules from CuAAC click-chemistry-based combinatorial libraries
X Wang, B Huang, X Liu, P Zhan - Drug Discovery Today, 2016 - Elsevier
Highlights•Advances in the combination of the CuAAC reaction with direct screening.•Before
library assembly, the bioisosteric potential of 1, 2, 3-triazole should be confirmed.•The …
library assembly, the bioisosteric potential of 1, 2, 3-triazole should be confirmed.•The …
Aryl group transfer from tetraarylborato anions to an electrophilic dicopper (I) center and mixed-valence μ-aryl dicopper (I, II) complexes
The synthesis of discrete, cationic binuclear μ-aryl dicopper complexes [Cu2 (μ-η1: η1-Ar)
DPFN] X (Ar= C6H5, 3, 5-(CF3) 2C6H3, and C6F5; DPFN= 2, 7-bis (fluoro-di (2-pyridyl) …
DPFN] X (Ar= C6H5, 3, 5-(CF3) 2C6H3, and C6F5; DPFN= 2, 7-bis (fluoro-di (2-pyridyl) …