Transcriptome sequencing reveals aberrant alternative splicing in Huntington's disease
Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder caused by
a CAG expansion in the gene-encoding Huntingtin (HTT). Transcriptome dysregulation is a …
a CAG expansion in the gene-encoding Huntingtin (HTT). Transcriptome dysregulation is a …
Changes in the expression of splicing factor transcripts and variations in alternative splicing are associated with lifespan in mice and humans
BP Lee, LC Pilling, F Emond, K Flurkey… - Aging cell, 2016 - Wiley Online Library
Dysregulation of splicing factor expression and altered alternative splicing are associated
with aging in humans and other species, and also with replicative senescence in cultured …
with aging in humans and other species, and also with replicative senescence in cultured …
Roles and regulation of epithelial splicing regulatory proteins 1 and 2 in epithelial–mesenchymal transition
EL Göttgens, PN Span, MM Zegers - … Review of Cell and Molecular Biology, 2016 - Elsevier
The transformation of polarized epithelial cells into cells with mesenchymal characteristics
by the morphogenetic process of epithelial–mesenchymal transition (EMT) is a well …
by the morphogenetic process of epithelial–mesenchymal transition (EMT) is a well …
RBM4–Nova1–SRSF6 splicing cascade modulates the development of brown adipocytes
JC Lin, YL Chi, HY Peng, YH Lu - Biochimica et Biophysica Acta (BBA) …, 2016 - Elsevier
Alternative splicing (AS) is a pivotal mechanism for the expansion of gene diversity, which
determines the cellular fate or specification. However, the effect of AS networks on brown …
determines the cellular fate or specification. However, the effect of AS networks on brown …
Redefining androgen receptor function: clinical implications in understanding prostate cancer progression and therapeutic resistance
M Paliouras, C Alvarado, M Trifiro - Prostate cancer–Leading …, 2016 - books.google.com
The current description of the function of the human androgen receptor (AR), as a
transcription factor directing androgen responsive gene expression, is limited in scope and …
transcription factor directing androgen responsive gene expression, is limited in scope and …
[PDF][PDF] Alternative splicing changes as drivers of cancer
Alternative splicing changes are frequently observed in cancer and are starting to be
recognized as important signatures for tumor progression and therapy. However, their …
recognized as important signatures for tumor progression and therapy. However, their …