Food allergy: immune mechanisms, diagnosis and immunotherapy

W Yu, DMH Freeland, KC Nadeau - Nature Reviews Immunology, 2016 - nature.com
Food allergy is a pathological, potentially deadly, immune reaction triggered by normally
innocuous food protein antigens. The prevalence of food allergies is rising and the standard …

[HTML][HTML] The mode of delivery affects the diversity and colonization pattern of the gut microbiota during the first year of infants' life: a systematic review

E Rutayisire, K Huang, Y Liu, F Tao - BMC gastroenterology, 2016 - Springer
Background The human gut is the habitat for diverse and dynamic microbial ecosystem. The
human microbiota plays a critical role in functions that sustain health and is a positive asset …

Impact of maternal intrapartum antibiotics, method of birth and breastfeeding on gut microbiota during the first year of life: a prospective cohort study

MB Azad, T Konya, RR Persaud… - … Journal of Obstetrics …, 2016 - Wiley Online Library
Objective Dysbiosis of the infant gut microbiota may have long‐term health consequences.
This study aimed to determine the impact of maternal intrapartum antibiotic prophylaxis (IAP) …

Early-life gut microbiome composition and milk allergy resolution

S Bunyavanich, N Shen, A Grishin, R Wood… - Journal of Allergy and …, 2016 - Elsevier
Background Gut microbiota may play a role in the natural history of cow's milk allergy.
Objective We sought to examine the association between early-life gut microbiota and the …

Molecular and cellular mechanisms of food allergy and food tolerance

RS Chinthrajah, JD Hernandez, SD Boyd… - Journal of Allergy and …, 2016 - Elsevier
Ingestion of innocuous antigens, including food proteins, normally results in local and
systemic immune nonresponsiveness in a process termed oral tolerance. Oral tolerance to …

Alterations in the gut microbiotas of children with food sensitization in early life

CC Chen, KJ Chen, MS Kong… - Pediatric Allergy and …, 2016 - Wiley Online Library
Background We hypothesized that food sensitization (FS) in children could be linked to
specific gut microbiota. The aim of our study is to quantify and evaluate differences in gut …

Food allergy: past, present and future

HA Sampson - Allergology International, 2016 - jstage.jst.go.jp
abstract Hippocrates is often credited with first recognizing that food could be responsible for
adverse symptoms and even death in some individuals, but it was not until the seminal …

[HTML][HTML] The microbiome, timing, and barrier function in the context of allergic disease

DR Wesemann, CR Nagler - Immunity, 2016 - cell.com
Allergic disease affects millions. Despite many advances in our understanding of the
immune system in the past century, the physiologic underpinning for the existence of allergy …

Evaluation of the effects of intrapartum antibiotic prophylaxis on newborn intestinal microbiota using a sequencing approach targeted to multi hypervariable 16S rDNA …

I Aloisio, A Quagliariello, S De Fanti, D Luiselli… - Applied microbiology …, 2016 - Springer
Different factors are known to influence the early gut colonization in newborns, among them
the perinatal use of antibiotics. On the other hand, the effect on the baby of the …

[HTML][HTML] The rise of food allergy: Environmental factors and emerging treatments

S Benedé, AB Blázquez, D Chiang, L Tordesillas… - …, 2016 - thelancet.com
Food allergy has rapidly increased in prevalence, suggesting an important role for
environmental factors in disease susceptibility. The immune response of food allergy is …