Outcomes in childhood following therapeutic hypothermia for neonatal hypoxic-ischemic encephalopathy (HIE)
G Natarajan, A Pappas, S Shankaran - Seminars in perinatology, 2016 - Elsevier
In this article, we review the childhood outcomes of neonates with birth depression and/or
hypoxic-ischemic encephalopathy. The outcomes of these children prior to the era of …
hypoxic-ischemic encephalopathy. The outcomes of these children prior to the era of …
[HTML][HTML] Perinatal brain damage: the term infant
Perinatal brain injury at term is common and often manifests with neonatal encephalopathy
including seizures. The most common aetiologies are hypoxic–ischaemic encephalopathy …
including seizures. The most common aetiologies are hypoxic–ischaemic encephalopathy …
Seizure burden and neurodevelopmental outcome in neonates with hypoxic–ischemic encephalopathy
L Kharoshankaya, NJ Stevenson… - … Medicine & Child …, 2016 - Wiley Online Library
Aim To examine the relationship between electrographic seizures and long‐term outcome in
neonates with hypoxic–ischemic encephalopathy (HIE). Method Full‐term neonates with HIE …
neonates with hypoxic–ischemic encephalopathy (HIE). Method Full‐term neonates with HIE …
[HTML][HTML] Moderate hypothermia within 6 h of birth plus inhaled xenon versus moderate hypothermia alone after birth asphyxia (TOBY-Xe): a proof-of-concept, open …
D Azzopardi, NJ Robertson, A Bainbridge… - The Lancet …, 2016 - thelancet.com
Background Moderate cooling after birth asphyxia is associated with substantial reductions
in death and disability, but additional therapies might provide further benefit. We assessed …
in death and disability, but additional therapies might provide further benefit. We assessed …
High-dose erythropoietin and hypothermia for hypoxic-ischemic encephalopathy: a phase II trial
OBJECTIVE: To determine if multiple doses of erythropoietin (Epo) administered with
hypothermia improve neuroradiographic and short-term outcomes of newborns with hypoxic …
hypothermia improve neuroradiographic and short-term outcomes of newborns with hypoxic …
[HTML][HTML] Association of brain injury and neonatal cytokine response during therapeutic hypothermia in newborns with hypoxic-ischemic encephalopathy
Background: Cytokines have been proposed as mediators of neonatal brain injury via
neuroinflammatory pathways triggered by hypoxia-ischemia. Limited data are available on …
neuroinflammatory pathways triggered by hypoxia-ischemia. Limited data are available on …
Birth asphyxia and hypoxic-ischemic brain injury in the preterm infant
AR Laptook - Clinics in perinatology, 2016 - perinatology.theclinics.com
Identification of infants! 36 weeks' gestation with perinatal hypoxia-ischemia or asphyxia has
allowed investigation of potential neuroprotective treatments. Therapeutic hypothermia is the …
allowed investigation of potential neuroprotective treatments. Therapeutic hypothermia is the …
Newborns referred for therapeutic hypothermia: association between initial degree of encephalopathy and severity of brain injury (what about the newborns with mild …
M Gagne-Loranger, M Sheppard, N Ali… - American journal of …, 2016 - thieme-connect.com
Objective The aim of this article was to describe the severity of brain injury and/or mortality in
a cohort of newborns referred for therapeutic hypothermia, in relation to the degree of …
a cohort of newborns referred for therapeutic hypothermia, in relation to the degree of …
Early MRI in neonatal hypoxic-ischaemic encephalopathy treated with hypothermia: prognostic role at 2-year follow-up
V Charon, M Proisy, G Bretaudeau, B Bruneau… - European journal of …, 2016 - Elsevier
The prognostic role of early MRI (≤ 6 days of life) is still uncertain in hypoxic-ischaemic
encephalopathy (HIE) treated with hypothermia. Objective To compare the prognostic value …
encephalopathy (HIE) treated with hypothermia. Objective To compare the prognostic value …
[HTML][HTML] Serum lactate, brain magnetic resonance imaging and outcome of neonatal hypoxic ischemic encephalopathy after therapeutic hypothermia
MC Chiang, R Lien, SM Chu, PH Yang, JJ Lin… - Pediatrics & …, 2016 - Elsevier
Background Serum lactate was used to predict the severity and outcome of neonatal hypoxic
ischemic encephalopathy (HIE) before the era of therapeutic hypothermia (TH). There is no …
ischemic encephalopathy (HIE) before the era of therapeutic hypothermia (TH). There is no …