Induced pluripotent stem cells (iPSC) and their differentiated derivatives offer a unique
source of human primary cells for toxicity screens. Here, we report on the comparative …

Valproic acid (VPA) is commonly prescribed as an anticonvulsant and mood stabilizer used
in the treatment of epilepsy and bipolar disorder. A recent study has demonstrated that VPA …

The negative impact of chemotherapy on cognitive function in cancer patients has gained
increasing attention in the last decade. Whilst the short-term acute effects on cognition are …

Cognitive deficit is a frequently reported side-effect of adjuvant chemotherapy. A large
number of animal studies has been performed to examine the neurobiological mechanisms …

Valproic acid (VPA), a commonly used antiepileptic drug, has been reported to cause
cognitive impairments in patients. In a previous study, using a rodent model, we showed that …

Clinical studies indicate that up to 70% of cancer patients who receive chemotherapy
experience cognitive impairment. The present study investigated environmental enrichment …

Self-reports of chemotherapy-related cognitive deficits (CRCDs) are more prevalent among
women than men, suggesting that women may be more vulnerable to the cognitive …

Chemotherapy treats many types of cancer effectively but it often causes side effects.
Chemotherapy works on active cells, such as cancer cells, and some healthy cells. Side …

Minocycline is purported to have neuroprotective properties in experimental models of some
human neurologic diseases, and has therefore been identified as a putative neuroprotectant …

Due to the increasing incidence of cancer during pregnancy, the need to better understand
long-term outcome after prenatal exposure to chemo-and/or radiotherapy has become more …