Traditional methods employed to discover new antibiotics are both a time-consuming and
financially-taxing venture. This has led researchers to mine existing libraries of clinical …

Terbinafine is a recommended therapeutic alternative for patients with sporotrichosis who
cannot use itraconazole due to drug interactions or side effects. Melanins are involved in …

The scourge of multidrug-resistant bacterial infections necessitates the urgent development
of novel antimicrobials to address this public health challenge. Drug repurposing is a proven …

The in vitro activities of caspofungin and micafungin were determined with and without
farnesol against Candida parapsilosis biofilms. Drug interactions were examined using the …

Auranofin is an FDA-approved gold-containing compound used for the treatment of
rheumatoid arthritis. Recent reports of antimicrobial activity against protozoa and bacteria …

This study was designed to assess the synergistic antimicrobial effect of phages combined
with antibiotics against Staphylococcus aureus. The phage-antibiotic synergy (PAS) effect …

The RNA-dependent RNA polymerase of influenza A virus comprises conserved and
independently-folded subdomains with defined functionalities. The N-terminal domain of the …

The development of a biolistic transformation protocol for Cryptococcus neoformans over 25
years ago ushered in a new era of molecular characterization of virulence in this previously …

Venoms of hymenopteran insects have attracted considerable interest as a source of
cationic antimicrobial peptides (AMPs). In the venom of the solitary bee Hylaeus signatus …

Ru (III) complexes with pyrazine derivatives: 2, 3-bis (2-pyridyl) pyrazine (DPP), pyrazine-2-
amidoxime (PAOX), pyrazine-2-thiocarboxamide (PTCA) and 2-amino-5-bromo-3 …