An integrated molecular landscape implicates the regulation of dendritic spine formation through insulin-related signalling in obsessive–compulsive disorder
I van de Vondervoort, G Poelmans, A Aschrafi… - Journal of Psychiatry and …, 2016 - jpn.ca
Background: Obsessive–compulsive disorder (OCD) is a neuropsychiatric disorder with
onset in childhood and is characterized by obsessions (recurrent, intrusive, persistent …
onset in childhood and is characterized by obsessions (recurrent, intrusive, persistent …
The need for inclusion of sex and age of onset variables in genetic association studies of obsessive–compulsive disorder: Overview
GF Mattina, M Steiner - Progress in Neuro-Psychopharmacology and …, 2016 - Elsevier
Obsessive–compulsive disorder (OCD) is a heterogeneous mental disorder that significantly
impairs an individual's functioning. The candidate gene approach has proven to be a useful …
impairs an individual's functioning. The candidate gene approach has proven to be a useful …
Modification of the association between early adversity and obsessive-compulsive disorder by polymorphisms in the MAOA, MAOB and COMT genes
NW McGregor, SMJ Hemmings, L Erdman… - Psychiatry …, 2016 - Elsevier
The monoamine oxidases (MAOA/B) and catechol-O-methyltransferase (COMT) enzymes
break down regulatory components within serotonin and dopamine pathways, and …
break down regulatory components within serotonin and dopamine pathways, and …
Catechol-O-Methyltransferase Gene Polymorphisms in Specific Obsessive–Compulsive Disorder Patients' Subgroups
FB Melo-Felippe, JB de Salles Andrade, IG Giori… - Journal of Molecular …, 2016 - Springer
Pharmacological data and animal models support the hypothesis that the dopaminergic
(DA) system is implicated in obsessive–compulsive disorder (OCD). Therefore, this case …
(DA) system is implicated in obsessive–compulsive disorder (OCD). Therefore, this case …
Voxelwise eigenvector centrality mapping of the human functional connectome reveals an influence of the catechol-O-methyltransferase val158met polymorphism on …
Functional connections between brain regions constitute the substrate of the human
functional connectome, whose topography has been discussed as an endophenotype for …
functional connectome, whose topography has been discussed as an endophenotype for …
Obsessive compulsive disorder
OCD is the fourth most common neuropsychiatric disorder with lifetime prevalence estimates
of 0.4–3.5%. Family and twin studies suggest a strong genetic component, and molecular …
of 0.4–3.5%. Family and twin studies suggest a strong genetic component, and molecular …
Obsessive-compulsive disorder
SE Stewart - … : Contemporary Surgical and Device-Based Treatments, 2016 - Springer
Obsessive-compulsive disorder (OCD) is a very common disease that affects approximately
2–3% of the general population across the lifespan [APA (Diagnostic and statistical manual …
2–3% of the general population across the lifespan [APA (Diagnostic and statistical manual …
A tetra-primer amplification refractory system technique for the cost-effective and novel genotyping of eight single-nucleotide polymorphisms of the catechol-O …
CK Wang, A Aleksic, MS Xu, RM Procyshyn… - Genetic Testing and …, 2016 - liebertpub.com
Aims: Catechol-O-methyltransferase (COMT) is an enzyme involved in the degradation of
catecholamine neurotransmitters. Due to its role in neurotransmitter flux, multiple COMT …
catecholamine neurotransmitters. Due to its role in neurotransmitter flux, multiple COMT …
[图书][B] How Do Genes Get Outside the Skin?: Mechanisms Underlying Gene× environment Interactions in Child Externalizing Problems
J Weeland - 2016 - pure.uva.nl
Chen, J., Lipska, BK, Halim, N., Ma, QD, Matsumoto, M., Melhem, S.,… Weinberger, DR
(2004). Functional analysis of genetic variation in catechol-O-methyltransferase (COMT) …
(2004). Functional analysis of genetic variation in catechol-O-methyltransferase (COMT) …
[图书][B] Genetics of obsessive-compulsive disorder: From phenotypes to pharmacogenetics
GCM Zai - 2016 - search.proquest.com
Background: Obsessive-compulsive disorder (OCD) is a debilitating neuropsychiatric
disorder that is characterized by a diverse clinical presentation. Evidence suggests genetic …
disorder that is characterized by a diverse clinical presentation. Evidence suggests genetic …