Past, present, and future of traumatic brain injury research

GWJ Hawryluk, MR Bullock - Neurosurgery Clinics, 2016 - neurosurgery.theclinics.com
Traumatic brain injury (TBI) of any severity has the potential to devastate the lives of patients
over minutes or hours. An intracranial hematoma can transform an active life to a vegetative …

[HTML][HTML] Induced pluripotent stem cell therapies for cervical spinal cord injury

VM Doulames, GW Plant - International journal of molecular sciences, 2016 - mdpi.com
Cervical-level injuries account for the majority of presented spinal cord injuries (SCIs) to
date. Despite the increase in survival rates due to emergency medicine improvements …

Aberrant LncRNA expression profile in a contusion spinal cord injury mouse model

Y Ding, Z Song, J Liu - BioMed Research International, 2016 - Wiley Online Library
Long noncoding RNAs (LncRNAs) play a crucial role in cell growth, development, and
various diseases related to the central nervous system. However, LncRNA differential …

[HTML][HTML] The association of palmitoylethanolamide with luteolin decreases autophagy in spinal cord injury

R Siracusa, I Paterniti, G Bruschetta, M Cordaro… - Molecular …, 2016 - Springer
Spinal cord injury (SCI) is a devastating condition of the central nervous system (CNS) often
resulting in severe functional impairment and for which there are not yet restorative …

Combining neuroprotective agents: effect of riluzole and magnesium in a rat model of thoracic spinal cord injury

NL Vasconcelos, ED Gomes, EP Oliveira, CJ Silva… - The Spine Journal, 2016 - Elsevier
Abstract Background Context Damage to the spinal cord can result in irreversible
impairments or complete loss of motor, sensory, and autonomic functions. Riluzole and …

Injury to the nervous system: a look into the ER

V Valenzuela, M Oñate, C Hetz, FA Court - Brain research, 2016 - Elsevier
Injury to the central or peripheral nervous systems leads to the loss of cognitive and/or
sensorimotor capabilities that still lack an effective treatment. Although injury to the nervous …

[HTML][HTML] Effects of hyperbaric oxygen therapy on RAGE and MCP-1 expression in rats with spinal cord injury

Y Wang, C Li, C Gao, Z Li, J Yang… - Molecular …, 2016 - spandidos-publications.com
The inflammatory response is an important source of secondary damage to neuronal tissue
in the spinal cord following spinal cord injury (SCI). Hyperbaric oxygen (HBO) therapy …

Effectiveness of minocycline and FK506 alone and in combination on enhanced behavioral and biochemical recovery from spinal cord injury in rats

M Ahmad, A Zakaria, KM Almutairi - Pharmacology Biochemistry and …, 2016 - Elsevier
Injury to the spinal cord results in immediate physical damage (primary injury) followed by a
prolonged posttraumatic inflammatory disorder (secondary injury). The present study aimed …

Imaging of spinal cord injury: acute cervical spinal cord injury, cervical spondylotic myelopathy, and cord herniation

K Talekar, M Poplawski, R Hegde, M Cox… - Seminars in Ultrasound …, 2016 - Elsevier
We review the pathophysiology and imaging findings of acute traumatic spinal cord injury
(SCI), cervical spondylotic myelopathy, and briefly review the much less common cord …

Geometrical variations in white and gray matter affect the biomechanics of spinal cord injuries more than the arachnoid space

L Fradet, PJ Arnoux, V Callot… - Advances in Mechanical …, 2016 - journals.sagepub.com
Traumatic spinal cord contusions lead to loss of quality of life, but their pathomechanisms
are not fully understood. Previous studies have underlined the contribution of the …