Highlights•The polygenic nature of neuro-affected disorders favors multi-targeted drug
design.•Revisions of major diagnostic systems support DMLs for neuropsychiatric …

Background Coexisting anxiety is common in major depressive disorder (MDD) and more
difficult to treat than depression without anxiety. This analysis assessed the efficacy, safety …

Background Anxiety symptoms are prevalent in major depressive disorder (MDD) and are
associated with greater illness severity, suicidality, impaired functioning and poor response …

The comorbidity between attention deficit hyperactivity disorder (ADHD) and major
depression is common. However, the influence of ADHD comorbidity in the response or …

Background Major depressive disorder (MDD) with concurrent anxiety symptoms may signal
a difficulttotreat patient. Brexpiprazole is a serotonin–dopamine activity modulator: a …

Previously, we found an anxiolytic effect of ziprasidone augmentation to escitalopram
(compared with placebo augmentation) in patients with depression in an 8-week …

Background: Anxiety and irritability often coexist in patients with major depressive disorder
(MDD). The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) …

目的探讨抑郁症患者伴焦虑症状的发生情况, 并从社会心理因素方面分析抑郁症伴焦虑症状的
影响因素. 方法采用汉密尔顿抑郁量表(Hamilton depression rating scale, HAMD) …

В статье изложены материалы, посвященные различным аспектам депрес сивных рас
ст ройств с точки зрения медикосоциаль но го значения и послед ствий, которые были …

1. ABSTRACT INTRODUCTION: Depressive and anxiety symptoms are two of the most
common presentation symptoms in primary and specialized care and are often comorbid …