Genetic models of focal epilepsies

M Boillot, S Baulac - Journal of neuroscience methods, 2016 - Elsevier
Focal epilepsies were for a long time thought to be acquired disorders secondary to cerebral
lesions. However, the important role of genetic factors in focal epilepsies is now well …

Secretion-positive LGI1 mutations linked to lateral temporal epilepsy impair binding to ADAM22 and ADAM23 receptors

E Dazzo, E Leonardi, E Belluzzi, S Malacrida… - PLoS …, 2016 - journals.plos.org
Autosomal dominant lateral temporal epilepsy (ADTLE) is a focal epilepsy syndrome caused
by mutations in the LGI1 gene, which encodes a secreted protein. Most ADLTE-causing …

[图书][B] Novel Roles of Metalloproteinases in Neurite Outgrowth and Synapse Formation

RL Sanz - 2016 - search.proquest.com
The establishment of the brain circuitry relies on the precise targeting and connectivity of
neuronal projections. Neurons respond to a vast repertoire of extracellular cues by …