Bioinformatic tools for microRNA dissection
Recently, microRNAs (miRNAs) have emerged as important elements of gene regulatory
networks. MiRNAs are endogenous single-stranded non-coding RNAs (∼ 22-nt long) that …
networks. MiRNAs are endogenous single-stranded non-coding RNAs (∼ 22-nt long) that …
Matrix metalloproteinases and their inhibitors in chronic obstructive pulmonary disease
Z Navratilova, V Kolek, M Petrek - Archivum immunologiae et therapiae …, 2016 - Springer
Chronic obstructive pulmonary disease (COPD) is characterised by irreversible airflow
limitation associated with chronic inflammation. Matrix metalloproteinases (MMPs) are …
limitation associated with chronic inflammation. Matrix metalloproteinases (MMPs) are …
miRNet-dissecting miRNA-target interactions and functional associations through network-based visual analysis
Y Fan, K Siklenka, SK Arora, P Ribeiro… - Nucleic acids …, 2016 - academic.oup.com
MicroRNAs (miRNAs) can regulate nearly all biological processes and their dysregulation is
implicated in various complex diseases and pathological conditions. Recent years have …
implicated in various complex diseases and pathological conditions. Recent years have …
[HTML][HTML] Characterization of long non-coding RNA-associated ceRNA network to reveal potential prognostic lncRNA biomarkers in human ovarian cancer
Accumulating evidence has underscored the important roles of long non-coding RNAs
(lncRNAs) acting as competing endogenous RNAs (ceRNAs) in cancer initiation and …
(lncRNAs) acting as competing endogenous RNAs (ceRNAs) in cancer initiation and …
A fast PC algorithm for high dimensional causal discovery with multi-core PCs
Discovering causal relationships from observational data is a crucial problem and it has
applications in many research areas. The PC algorithm is the state-of-the-art constraint …
applications in many research areas. The PC algorithm is the state-of-the-art constraint …
[HTML][HTML] Construction and analysis of dysregulated lncRNA-associated ceRNA network identified novel lncRNA biomarkers for early diagnosis of human pancreatic …
It is increasing evidence that ceRNA activity of long non-coding RNAs (lncRNAs) played
critical roles in both normal physiology and tumorigenesis. However, functional roles and …
critical roles in both normal physiology and tumorigenesis. However, functional roles and …
Integrated analysis of dysregulated ncRNA and mRNA expression profiles in humans exposed to carbon nanotubes
AA Shvedova, N Yanamala, ER Kisin, TO Khailullin… - PloS one, 2016 - journals.plos.org
Background As the application of carbon nanotubes (CNT) in consumer products continues
to rise, studies have expanded to determine the associated risks of exposure on human and …
to rise, studies have expanded to determine the associated risks of exposure on human and …
[HTML][HTML] microRNA-guided diagnostics in clinical samples
miRNA-guided diagnostics is a powerful molecular approach for evaluating clinical samples
through miRNA detection and/or visualization. To date, this approach has been successfully …
through miRNA detection and/or visualization. To date, this approach has been successfully …
Identifying cancer subtypes from miRNA-TF-mRNA regulatory networks and expression data
Background Identifying cancer subtypes is an important component of the personalised
medicine framework. An increasing number of computational methods have been …
medicine framework. An increasing number of computational methods have been …
Anti-inflammatory effects of miR-21 in the macrophage response to peritonitis
RE Barnett, DJ Conklin, L Ryan… - Journal of Leucocyte …, 2016 - academic.oup.com
We investigated the role of microRNA-21 in the macrophage response to peritonitis;
microRNA-21 expression increases in peritoneal macrophages after lipopolysaccharide …
microRNA-21 expression increases in peritoneal macrophages after lipopolysaccharide …