Current diagnostic and treatment strategies for specific dilated cardiomyopathies: a scientific statement from the American Heart Association
The first classification on this topic categorized cardiomyopathies as heart muscle diseases
with dilated (DCM), hypertrophic, restrictive, arrhythmogenic right ventricular (ARVC), or …
with dilated (DCM), hypertrophic, restrictive, arrhythmogenic right ventricular (ARVC), or …
Cardiac embryology and molecular mechanisms of congenital heart disease: a primer for anesthesiologists
B Kloesel, JA DiNardo, SC Body - Anesthesia & Analgesia, 2016 - journals.lww.com
Congenital heart disease is diagnosed in 0.4% to 5% of live births and presents unique
challenges to the pediatric anesthesiologist. Furthermore, advances in surgical …
challenges to the pediatric anesthesiologist. Furthermore, advances in surgical …
[HTML][HTML] Genetic testing in congenital heart disease: A clinical approach
MA Chaix, G Andelfinger, P Khairy - World journal of cardiology, 2016 - ncbi.nlm.nih.gov
Congenital heart disease (CHD) is the most common type of birth defect. Traditionally, a
polygenic model defined by the interaction of multiple genes and environmental factors was …
polygenic model defined by the interaction of multiple genes and environmental factors was …
Utilization of whole exome sequencing to identify causative mutations in familial congenital heart disease
Background—Congenital heart disease (CHD) is the most common type of birth defect with
family-and population-based studies supporting a strong genetic cause for CHD. The goal of …
family-and population-based studies supporting a strong genetic cause for CHD. The goal of …
[HTML][HTML] Genetics of congenital heart disease: the contribution of the noncoding regulatory genome
AV Postma, CR Bezzina, VM Christoffels - Journal of human genetics, 2016 - nature.com
Congenital heart disease (CHD) is the most common type of birth defect. The advent of
corrective cardiac surgery and the increase in knowledge concerning the longitudinal care …
corrective cardiac surgery and the increase in knowledge concerning the longitudinal care …
[HTML][HTML] The hypertrabeculated (noncompacted) left ventricle is different from the ventricle of embryos and ectothermic vertebrates
Ventricular hypertrabeculation (noncompaction) is a poorly characterized condition
associated with heart failure. The condition is widely assumed to be the retention of the …
associated with heart failure. The condition is widely assumed to be the retention of the …
Ebstein anomaly, left ventricular non‐compaction, and early onset heart failure associated with a de novo α‐tropomyosin gene mutation
AM Kelle, SJ Bentley, LO Rohena… - American journal of …, 2016 - Wiley Online Library
Ebstein anomaly of the tricuspid valve (EA) can be associated with left ventricular non‐
compaction (LVNC), a rare congenital cardiomyopathy. We report a 2 year‐old female with …
compaction (LVNC), a rare congenital cardiomyopathy. We report a 2 year‐old female with …
[HTML][HTML] Genetic variants in isolated Ebstein anomaly implicated in myocardial development pathways
RJ Sicko, ML Browne, SL Rigler, CM Druschel, G Liu… - PloS one, 2016 - journals.plos.org
Ebstein anomaly (EA) is a rare heart defect in which the tricuspid valve is malformed and
displaced. The tricuspid valve abnormalities can lead to backflow of blood from the right …
displaced. The tricuspid valve abnormalities can lead to backflow of blood from the right …
The pathogenicity of genetic variants previously associated with left ventricular non‐compaction
Background Left ventricular non‐compaction (LVNC) is a rare cardiomyopathy. Many
genetic variants have been associated with LVNC. However, the number of the previous …
genetic variants have been associated with LVNC. However, the number of the previous …
Dilated cardiomyopathy
JA Jansweijer, R Hershberger… - Clinical …, 2016 - Springer
Dilated cardiomyopathy (DCM) is characterized by impaired left ventricular (LV) systolic
function and left ventricular dilation. Remarkable progress has been made in understanding …
function and left ventricular dilation. Remarkable progress has been made in understanding …