Besides its important role in embryonic development and homeostatic self-renewal in adult
tissues, Wnt/β-catenin signaling exerts both anti-inflammatory and proinflammatory …

It is well documented that ionizing radiation (IR) activates the transcription factor (NF-κB)
which is a trigger for resistance cancer cells to treatment. It is involved in activation of pro …

The excessive or prolonged production of inflammatory mediators can result in numerous
chronic diseases, such as rheumatoid arthritis, atherosclerosis, diabetes, and cancer …

This review portraits FK506 binding protein (FKBP) 51 as “reactivity protein” and collates
recent publications to develop the concept of FKBP51 as contributor to different levels of …

As an important nutrient source in large area of world, the composition and nutritional value
of goat milk are not well deliberated. Detailed annotation of protein composition is essential …

The nuclear factor-κB (NF-κB) transcription factor family plays critical roles in the
pathophysiology of hematologic neoplasias, including multiple myeloma. The current review …

The multifaceted involvement of the active vitamin D metabolite 1, 25-dihydroxyvitamin D3
(henceforth referred to by the synonyms 1, 25 (OH) 2D3, calcitriol or vitamin D) in blunting …

Aberrant activation of oncogenic signaling pathways plays a pivotal role in tumor initiation
and progression. The purpose of the present study was to investigate the chemopreventive …

This study was aimed to research the effects of IL-15 on inducing inflammatory infiltration of
macrophages in polymyositis (PM) through the NF-kB pathway, and whether IL-15 was able …

The persistence of HIV in resting memory CD4+ T cells at a latent state is considered as the
major barrier on the path to achieve a cure for HIV. Proteasome inhibitors (PIs) were …