Cocrystal is a concept of the supramolecular chemistry which is gaining the extensive
interest of researchers from pharmaceutical and chemical sciences and of drug regulatory …

Cocrystals, a long known but understudied class of crystalline solids, have attracted interest
from crystal engineers and pharmaceutical scientists in the past decade and are now an …

Abstract A novel cocrystal (NEX‐1) of CL‐20 and MDNT is presented herein. The CL‐20:
MDNT cocrystal, obtained in high yield by resonant acoustic mixing, shows new properties …

Solid-state mechanochemical grinding is important for promoting cocrystal formation,
particularly in the design of new solids in the pharmaceutical industry. Pharmaceutical …

This chapter provides a high‐level overview of pharmaceutical solid‐state landscape and
introduces a field of computational modeling in Drug Development, also called …

Purpose Solvates are mainly undesired by-products during the pharmaceutical development
of new drugs. In addition, solvate formation may also distort solubility measurements. The …

The cocrystallization of salicylamide (2-hydroxybenzamide, SMD) and ethenzamide (2-
ethoxybenzamide, EMD) with aromatic carboxylic acids was examined both experimentally …

Conductor‐like screening model for realistic solvation (COSMO‐RS)'s unique combination
of quantum chemistry and surface segment–based statistical thermodynamics allows for …

Simvastatin (SV) is the drug of choice for hypercholesterolemia, which belong to the BCS
class II as very troubled with drug solubility. We report the novelty of increased solubility and …

The highly polymorphic compound ROY, notorious for the colour of its crystals, was the
subject of an optimised high-throughput ultrasound-based co-crystal screen. This screen …