The milk fat globule membrane (MFGM) in breast milk contains many bioactive components.
Infant formulas traditionally have been devoid of the MFGM fraction, but dairy technology …

Objective: Choline is an essential nutrient and plays a critical role in brain development, cell
signaling, nerve impulse transmission, and lipid transport and metabolism. This analysis …

Introduction The pro-atherosclerotic metabolite trimethylamine-N-oxide (TMAO) is a risk
factor for incident cardiovascular events and a potentially modifiable mediator of chronic …

Down syndrome (DS), caused by trisomy of chromosome 21, is marked by intellectual
disability (ID) and early onset of Alzheimer's disease (AD) neuropathology including …

Choline is a dietary component and precursor of acetylcholine, a crucial neurotransmitter for
memory-related brain functions. In two double-blind, placebo-controlled cross-over …

Plasma concentrations of choline, betaine, and dimethylglycine provide valuable information
on the flow of methyl groups in key biological processes, particularly during folate deficiency …

The present study was aimed to evaluate the effects of feeding different levels and sources
of methionine (DL-Methionine and methionine hydroxy analogue, MHA) on growth …

Diethanolamine (DEA) has been found to produce liver and kidney tumors in mice following
lifetime dermal exposures. Data regarding the mode of action by which DEA produces these …

Aging and age-related diseases in humans are mainly caused by oxidative stress through
over-production of reactive oxygen species (ROS). In our previous study, multi-micronutrient …

Background Choline is an important source of phospholipids and methyl groups in
mammalian cells. High demands for methyl and phospholipids in malignant cells suggest …