Use of cell-penetrating peptides in dendritic cell-based vaccination

S Lim, JH Koo, JM Choi - Immune network, 2016 - synapse.koreamed.org
Cell-penetrating peptides (CPPs) are short amino acids that have been widely used to
deliver macromolecules such as proteins, peptides, DNA, or RNA, to control cellular …

[HTML][HTML] Dendritic cell-based cancer immunotherapy for colorectal cancer

M Kajihara, K Takakura, T Kanai, Z Ito… - World journal of …, 2016 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is one of the most common cancers and a leading cause of cancer-
related mortality worldwide. Although systemic therapy is the standard care for patients with …

Immunological characterization of whole tumour lysate-loaded dendritic cells for cancer immunotherapy

V Rainone, C Martelli, L Ottobrini, M Biasin, M Borelli… - PloS one, 2016 - journals.plos.org
Introduction Dendritic cells play a key role as initiators of T-cell responses, and even if
tumour antigen-loaded dendritic cells can induce anti-tumour responses, their efficacy has …

[HTML][HTML] Advances in inducing adaptive immunity using cell-based cancer vaccines: clinical applications in pancreatic cancer

M Kajihara, K Takakura, T Kanai, Z Ito… - World Journal of …, 2016 - ncbi.nlm.nih.gov
The incidence of pancreatic ductal adenocarcinoma (PDA) is on the rise, and the prognosis
is extremely poor because PDA is highly aggressive and notoriously difficult to treat …

Extracorporeal removal of microvesicular particles

T Ichim, RH Tullis - US Patent 9,364,601, 2016 - Google Patents
The invention described herein teaches methods of removing microvesicular particles,
which include but are not limited to exosomes, from the systemic circulation of a Subject in …

Vaccines and Immunostimulants

J Schlom, JL Gulley, JW Hodge - Holland‐Frei Cancer …, 2016 - Wiley Online Library
Overview The US Food and Drug Administration approvals of the prostate cancer
therapeutic vaccine sipuleucel‐T, the checkpoint inhibitor anti‐CTLA‐4 and anti‐PD‐L1/PD …

Etude des altérations du métabolisme de la sphingosine-1-phosphate dans le mélanome cutané: rôle sur l'infiltration et la polarisation des macrophages associés aux …

M Mrad - 2016 - theses.hal.science
L'infiltration des mélanomes par les macrophages (TAM) est souvent corrélée à un mauvais
pronostic. Cependant, les mécanismes qui régulent le recrutement et la fonction de ces …