The ability to control cell behaviour, cell fate and simulate reliable tissue models in vitro
remains a significant challenge yet is crucial for various applications of high throughput …

Nuclear spreading plays a crucial role in stem cell fate determination. In previous works, we
reported evidence of multipotency maintenance for mesenchymal stromal cells cultured on …

We present three-dimensional (3D) finite element (FE) models of single, mesenchymal stem
cells (MSCs), generated from images obtained by optical phase-contrast microscopy and …

Computational cell mechanics models are dependent on cell morphology. Most studies of
cell mechanics use an idealized geometry or a cell-specific approach. These approaches do …

Background: Cholesterol content alters cell membrane stiffness and lateral lipid and protein
diffusion. It is an important risk factor in diseases like atherosclerosis, due to its active uptake …

Mechanotransduction of haemodynamic forces by endothelial cells is a focal determinant of
atherosclerosis. Endothelial cells may be a potential target for treatment and diagnosis of …