[HTML][HTML] First-line afatinib versus chemotherapy in patients with non–small cell lung cancer and common epidermal growth factor receptor gene mutations and brain …

M Schuler, YL Wu, V Hirsh, K O'Byrne… - Journal of Thoracic …, 2016 - Elsevier
Introduction Metastatic spread to the brain is common in patients with non–small cell lung
cancer (NSCLC), but these patients are generally excluded from prospective clinical trials …

[HTML][HTML] Epidermal growth factor receptor tyrosine kinase inhibitors for the treatment of central nervous system metastases from non-small cell lung cancer: the present …

C Proto, M Imbimbo, R Gallucci, A Brissa… - … lung cancer research, 2016 - ncbi.nlm.nih.gov
Lung cancer is one of the major causes of cancer related mortality worldwide. Brain
metastases (BM) complicate clinical evolution of non-small cell lung cancer (NSCLC) in …

The role of EGFR-TKI for leptomeningeal metastases from non-small cell lung cancer

X Yufen, S Binbin, C Wenyu, L Jialiang, Y Xinmei - Springerplus, 2016 - Springer
Leptomeningeal metastasis (LM) is a terminal event in the development of non-small cell
lung cancer (NSCLC). It has a poor prognosis with median survival of 1.9 months if …

Impact of whole brain radiation therapy on CSF penetration ability of Icotinib in EGFR-mutated non-small cell lung cancer patients with brain metastases: results of …

L Zhou, J He, W Xiong, Y Liu, J Xiang, Q Yu, M Liang… - Lung Cancer, 2016 - Elsevier
Objectives Whole-brain radiation therapy (WBRT) and epidermal growth factor receptor
tyrosine kinase inhibitors (EGFR-TKIs) are both treatment options for EGFR-mutated non …

Tyrosine kinase inhibitors for EGFR-and ALK-mutated non-small cell lung cancer

JR Thompson, SP Menon, GK Dy - Admet and Dmpk, 2016 - hrcak.srce.hr
Sažetak Discovery of the epidermal growth receptor (EGFR) activating mutations and
anaplastic lymphoma kinase (ALK) rearrangements has expanded the therapeutic …

Complete remission through icotinib treatment in Non-small cell lung cancer epidermal growth factor receptor mutation patient with brain metastasis: A case report

T Wang, R Wang, Z Dong, N Liang, P Chang - Open Medicine, 2016 - degruyter.com
Brain metastasis (BM) has been universally recognized as a poor prognostic factor in non-
small cell lung cancer (NSCLC). Epidermal growth factor receptor (EGFR) tyrosine kinase …

[引用][C] 大剂量EGFR-TKI 治疗非小细胞肺癌脑转移的研究进展

李玉, 张艳, 冯秀丽 - 国际呼吸杂志, 2016

[引用][C] 厄洛替尼同步全脑放疗二线治疗无症状的多发性肺腺癌脑转移患者的临床疗效观察

龙建林, 杨宁, 贺竞 - 肿瘤学杂志, 2016

[引用][C] 非小细胞肺癌脑转移的治疗进展

王卓, 张玉宇, 张兰广, 龚守良, 董丽华 - 中国老年学杂志, 2016

[引用][C] Treatment with high-dose, weekly erlotinib in EGFR-mutated NSCLC-patients with extra-cranial progressive disease on standard-dose EGFR-TKIs

JL Kuiper, DAM Heideman, E Thunnissen, AW van Wijk…