Myeloperoxidase inhibition improves ventricular function and remodeling after experimental myocardial infarction

M Ali, B Pulli, G Courties, B Tricot, M Sebas… - JACC: Basic to …, 2016 - jacc.org
PF-1355 is an oral myeloperoxidase (MPO) inhibitor that successfully decreased elevated
MPO activity in mouse myocardial infarction models. Short duration PF-1355 treatment for 7 …

Wearable cardioverter-defibrillator therapy for the prevention of sudden cardiac death: a science advisory from the American Heart Association

JP Piccini Sr, LA Allen, PJ Kudenchuk, RL Page… - Circulation, 2016 - Am Heart Assoc
Sudden cardiac death (SCD) accounts for> 300 000 deaths in the United States annually. 1
Although the majority of these deaths occur in low-risk populations2 in which aggressive …

Mortality pattern and cause of death in a long-term follow-up of patients with STEMI treated with primary PCI

AD Hosseiny, S Moloi, J Chandrasekhar, A Farshid - Open heart, 2016 - openheart.bmj.com
Objective We aimed to assess the pattern of mortality and cause of death in a cohort of
patients with ST-segment elevation myocardial infarction (STEMI) treated with primary …

Time to reperfusion in ST-segment elevation myocardial infarction patients with vs. without pre-hospital mobile telemedicine 12-lead electrocardiogram transmission

S Kawakami, Y Tahara, T Noguchi, N Yagi… - Circulation …, 2016 - jstage.jst.go.jp
Background: Prehospital ECG improves survival following ST-segment elevation myocardial
infarction (STEMI). Although a new International Consensus on Cardiopulmonary …

Myocardial infarction causes transient cholinergic transdifferentiation of cardiac sympathetic nerves via gp130

A Olivas, RT Gardner, L Wang… - Journal of …, 2016 - Soc Neuroscience
Sympathetic and parasympathetic control of the heart is a classic example of norepinephrine
(NE) and acetylcholine (ACh) triggering opposing actions. Sympathetic NE increases heart …

Cardioprotective effects of baicalein on heart failure via modulation of Ca2+ handling proteins in vivo and in vitro

F Zhao, L Fu, W Yang, Y Dong, J Yang, S Sun, Y Hou - Life sciences, 2016 - Elsevier
Aims Baicalein is a widely used Chinese herbal medicine extracted from Labiatae plants
Scutellaria baicalensis Georgi's dry root, which has multiple pharmacological activities …

Predictors of sudden cardiac death in doberman pinschers with dilated cardiomyopathy

L Klüser, PJ Holler, J Simak, G Tater… - Journal of Veterinary …, 2016 - Wiley Online Library
Background Doberman Pinschers with dilated cardiomyopathy (DCM) are at high risk of
sudden cardiac death (SCD). Risk factors for SCD are poorly defined. Aim To assess cardiac …

Programmed ventricular stimulation to risk stratify for early cardioverter-defibrillator implantation to prevent tachyarrhythmias following acute myocardial infarction …

S Zaman, AJ Taylor, M Stiles, C Chow… - Heart, Lung and …, 2016 - Elsevier
The 'Programmed Ventricular Stimulation to Risk Stratify for Early Cardioverter-Defibrillator
Implantation to Prevent Tachyarrhythmias following Acute Myocardial Infarction'(PROTECT …

Sudden cardiac death after non–ST-segment elevation acute coronary syndrome

PL Hess, DM Wojdyla, SM Al-Khatib… - JAMA …, 2016 - jamanetwork.com
Importance In the current therapeutic era, the risk for sudden cardiac death (SCD) after non–
ST-segment elevation acute coronary syndrome (NSTE ACS) has not been characterized …

ST-elevation myocardial infarction with reduced left ventricular ejection fraction: Insights into persisting left ventricular dysfunction. A pPCI-registry analysis

D Stolfo, M Cinquetti, M Merlo, S Santangelo… - International journal of …, 2016 - Elsevier
Primary percutaneous coronary intervention (pPCI) largely reduced the rate of left ventricular
(LV) dysfunction after ST-segment elevation acute myocardial infarction (STEMI). Though LV …