The chemistry of neurodegeneration: kinetic data and their implications

M Pavlin, M Repič, R Vianello, J Mavri - Molecular neurobiology, 2016 - Springer
We collected experimental kinetic rate constants for chemical processes responsible for the
development and progress of neurodegeneration, focused on the enzymatic and non …

[HTML][HTML] Isothiocyanates are promising compounds against oxidative stress, neuroinflammation and cell death that may benefit neurodegeneration in Parkinson's …

G Sita, P Hrelia, A Tarozzi, F Morroni - International Journal of Molecular …, 2016 - mdpi.com
Parkinson's disease (PD) is recognized as the second most common neurodegenerative
disorder and is characterized by a slow and progressive degeneration of dopaminergic …

[HTML][HTML] Inhibition of inflammation and iNOS improves lymphatic function in obesity

JS Torrisi, GE Hespe, DA Cuzzone, IL Savetsky… - Scientific reports, 2016 - nature.com
Although recent studies have shown that obesity decreases lymphatic function, the cellular
mechanisms regulating this response remain unknown. In the current study, we show that …

[HTML][HTML] Anti‑inflammatory potential of total saponins derived from the roots of Panax ginseng in lipopolysaccharide‑activated RAW 264.7 macrophages

KJ Jang, SH Choi, GJ Yu, SH Hong… - Experimental and …, 2016 - spandidos-publications.com
Ginseng, the root of Panax ginseng CA Meyer (Araliaceae), is a widely known traditional
medicine that has been utilized throughout Asia for several thousand years. Ginseng …

[HTML][HTML] Anti-inflammatory properties of flavone di-C-glycosides as active principles of Camellia mistletoe, Korthalsella japonica

MK Kim, KJ Yun, DH Lim, J Kim… - Biomolecules & …, 2016 - ncbi.nlm.nih.gov
The chemical components and biological activity of Camellia mistletoe, Korthalsella
japonica (Loranthaceae) are relatively unknown compared to other mistletoe species …

Apocyanin, a microglial NADPH oxidase inhibitor prevents dopaminergic neuronal degeneration in lipopolysaccharide-induced Parkinson's disease model

N Sharma, B Nehru - Molecular neurobiology, 2016 - Springer
Microglia-associated inflammatory processes have been strongly implicated in the
development and progression of Parkinson's disease (PD). Specifically, microglia are …

Protective Role of Flavonoids and Lipophilic Compounds from Jatropha platyphylla on the Suppression of Lipopolysaccharide (LPS)-Induced Inflammation in …

DL Ambriz-Pérez, WY Bang, V Nair… - Journal of agricultural …, 2016 - ACS Publications
Seventeen polyphenols (eg, apigenin, genistein, and luteolin glycosides) and 11 lipophilic
compounds (eg, fatty acids, sterols, and terpenes) were detected by LC-MS/MS-ESI and GC …

[HTML][HTML] Hyperbaric oxygen preconditioning: a reliable option for neuroprotection

Q Hu, A Manaenko, N Matei, Z Guo, T Xu… - Medical gas …, 2016 - journals.lww.com
Brain injury is the leading cause of death and disability worldwide and clinically there is no
effective therapy for neuroprotection. Hyperbaric oxygen preconditioning (HBO-PC) has …

Kinin peptides enhance inflammatory and oxidative responses promoting apoptosis in a Parkinson's disease cellular model

A Niewiarowska-Sendo, A Kozik… - Mediators of …, 2016 - Wiley Online Library
Kinin peptides ubiquitously occur in nervous tissue and participate in inflammatory
processes associated with distinct neurological disorders. These substances have also …

Altered arginine metabolism in cells transfected with human wild-type beta amyloid precursor protein (βAPP)

H Jęśko, A Wilkaniec, M Cieślik… - Current Alzheimer …, 2016 - ingentaconnect.com
Alterations of enzymes linked to arginine metabolism have been recently implicated in
Alzheimer's disease (AD). Despite strong association of arginine changes with nitric oxide …