Analysis of human breast milk cells: gene expression profiles during pregnancy, lactation, involution, and mastitic infection

JA Sharp, C Lefèvre, A Watt, KR Nicholas - Functional & Integrative …, 2016 - Springer
The molecular processes underlying human milk production and the effects of mastitic
infection are largely unknown because of limitations in obtaining tissue samples …

The BH3-only protein BIM contributes to late-stage involution in the mouse mammary gland

F Schuler, F Baumgartner, V Klepsch… - Cell Death & …, 2016 - nature.com
After cessation of lactation, involution of the mouse mammary gland proceeds in two distinct
phases, a reversible and an irreversible one, which leads to the death and removal of …

[HTML][HTML] Cell survival signaling in the bovine mammary gland during the transition from lactation to involution

K Singh, I Vetharaniam, JM Dobson, M Prewitz… - Journal of Dairy …, 2016 - Elsevier
In dairy cows, mammary gland involution, and thus a decline in milk production, occurs
following peak lactation. To examine the cell signaling pathways regulating involution of the …

Hypothyroidism advances mammary involution in lactating rats through inhibition of PRL signaling and induction of LIF/STAT3 mRNAs

FCV Arboccó, CV Sasso, EA Actis, RW Carón… - Molecular and cellular …, 2016 - Elsevier
Thyroid diseases have deleterious effects on lactation, litter growth and survival, and hinder
the suckling-induced hormone release, leading in the case of hyperthyroidism, to premature …

Differential cytokine sensitivities of STAT5-dependent enhancers rely on Stat5 autoregulation

M Willi, KH Yoo, C Wang, Z Trajanoski… - Nucleic Acids …, 2016 - academic.oup.com
Cytokines utilize the transcription factor STAT5 to control cell-specific genes at a larger scale
than universal genes, with a mechanistic explanation yet to be supplied. Genome-wide …

Lineage-specific and non-specific cytokine-sensing genes respond differentially to the master regulator STAT5

X Zeng, M Willi, HY Shin, L Hennighausen, C Wang - Cell reports, 2016 - cell.com
STAT5, a member of the family of signal transducers and activators of transcription, senses
cytokines and controls the biology of cell lineages, including mammary, liver, and T cells …

Reduced use of glucose by normoxic cow's mammary gland under acute inflammation: an example of homeostatic aerobic glycolysis

N Silanikove, F Shapiro, U Merin, Y Lavon, SE Blum… - RSC …, 2016 - pubs.rsc.org
The concentrations of glucose and glucose-derived carbons in milk reflect their
concentrations in the mammary epithelial cell cytosol. We hypothesized that the sharp …

Augmentation of gonadotropin-releasing hormone receptor expression in the post-lactational mammary tissues of rats

R Terashima, T Laoharatchatathanin… - … of Reproduction and …, 2016 - jstage.jst.go.jp
Gonadotropin-releasing hormone (GnRH) is a neurohormone of the hypothalamus
controlling pituitary gonadotropin secretion and hence gametogenesis. While it has also …

Impacto del sistema renina angiotensina en la involución mamaria y en la progresión tumoral

N Cambados - 2016 - bibliotecadigital.exactas.uba.ar
El desarrollo de la glándula mamaria es un proceso dinámico que involucra ciclos
continuos de proliferación, diferenciación y regresión. Luego de la lactancia, comienza la …

Context dependent roles of microRNA-150-5p in normal mammary gland development and breast cancer

RE Heinz - 2016 - search.proquest.com
Profiling of RNA in mouse mammary epithelial cells (MECs) isolated during pregnancy and
lactation revealed that most differentially expressed microRNA (miRNA) precipitously …