Influences of BRAF inhibitors on the immune microenvironment and the rationale for combined molecular and immune targeted therapy

SM Reddy, A Reuben, JA Wargo - Current oncology reports, 2016 - Springer
The identification of key driver mutations in melanoma has led to the development of
targeted therapies aimed at BRAF and MEK, but responses are often limited in duration …

miRNAs in melanoma: tumor suppressors and oncogenes with prognostic potential

M Wozniak, A Mielczarek, M Czyz - Current medicinal …, 2016 - ingentaconnect.com
MicroRNAs (miRNAs), which are small non-coding RNA molecules that post-
transcriptionally regulate the expression of target genes, control the vast majority of cellular …

[HTML][HTML] Regulation of melanoma progression through the TCF4/miR-125b/NEDD9 cascade

F Rambow, A Bechadergue, F Luciani, G Gros… - Journal of Investigative …, 2016 - Elsevier
Melanoma progression from a primary lesion to a distant metastasis is a complex process
associated with genetic alterations, epigenetic modifications, and phenotypic switches …