[HTML][HTML] Hepatitis E seroprevalence in Europe: a meta-analysis

J Hartl, B Otto, RG Madden, G Webb, KL Woolson… - Viruses, 2016 - mdpi.com
There have been large numbers of studies on anti-HEV IgG seroprevalence in Europe,
however, the results of these studies have produced high variability of seroprevalence rates …

Hepatitis E virus and neurological injury

HR Dalton, N Kamar, JJJ Van Eijk, BN Mclean… - Nature Reviews …, 2016 - nature.com
Hepatitis E is hyperendemic in many developing countries in Asia and Africa, and is caused
by hepatitis E virus (HEV) genotypes 1 and 2, which are spread via the faecal–oral route by …

Distinct entry mechanisms for nonenveloped and quasi-enveloped hepatitis E viruses

X Yin, C Ambardekar, Y Lu, Z Feng - Journal of virology, 2016 - Am Soc Microbiol
The hepatitis E virus (HEV) sheds into feces as nonenveloped virions but circulates in the
blood in a membrane-associated, quasi-enveloped form (eHEV). Since the eHEV virions …

Update on hepatitis E virology: Implications for clinical practice

Y Debing, D Moradpour, J Neyts, J Gouttenoire - Journal of hepatology, 2016 - Elsevier
Hepatitis E virus (HEV) is a positive-strand RNA virus transmitted by the fecal-oral route. The
7.2 kb genome encodes three open reading frames (ORF) which are translated into (i) the …

[HTML][HTML] Hepatitis E pathogenesis

S Lhomme, O Marion, F Abravanel, S Chapuy-Regaud… - Viruses, 2016 - mdpi.com
Although most hepatitis E virus (HEV) infections are asymptomatic, some can be severe,
causing fulminant hepatitis and extra-hepatic manifestations, including neurological and …

Extrahepatic manifestations of hepatitis E virus

N Kamar, O Marion, F Abravanel, J Izopet… - Liver …, 2016 - Wiley Online Library
Hepatitis E virus can cause acute, fulminant and chronic hepatitis and has been associated
with a range of extrahepatic manifestations. Guillain–Barré syndrome, neuralgic amyotrophy …

Hepatitis E virus in industrialized countries: the silent threat

P Clemente-Casares, C Ramos-Romero… - BioMed research …, 2016 - Wiley Online Library
Hepatitis E virus (HEV) is the main cause of acute viral hepatitis worldwide. Its presence in
developing countries has been documented for decades. Developed countries were …

Mutation in the hepatitis E virus polymerase and outcome of ribavirin therapy

S Lhomme, N Kamar, F Nicot, J Ducos… - Antimicrobial agents …, 2016 - Am Soc Microbiol
Hepatitis E virus (HEV) can lead to chronic infection in solid-organ transplant patients.
Ribavirin is efficient for treatment of chronically infected patients. Recently, the1634R …

[HTML][HTML] Hepatitis E virus mutations: functional and clinical relevance

H van Tong, NX Hoan, B Wang, H Wedemeyer… - …, 2016 - thelancet.com
Hepatitis E virus (HEV) infection is a major cause of acute hepatitis and affects more than 20
million individuals, with three million symptomatic cases and 56,000 recognized HEV …

[HTML][HTML] Acute hepatitis E: two sides of the same coin

J Hartl, MH Wehmeyer, S Pischke - Viruses, 2016 - mdpi.com
The relevance of acute hepatitis E virus (HEV) infections has been underestimated for a long
time. In the past, HEV infection had been interpreted falsely as a disease limited to the …