Epigenetics and inheritance of phenotype variation in livestock

KA Triantaphyllopoulos, I Ikonomopoulos… - Epigenetics & …, 2016 - Springer
Epigenetic inheritance plays a crucial role in many biological processes, such as gene
expression in early embryo development, imprinting and the silencing of transposons. It has …

Epigenomics in marine fishes

DCH Metzger, PM Schulte - Marine Genomics, 2016 - Elsevier
Epigenetic mechanisms are an underappreciated and often ignored component of an
organism's response to environmental change and may underlie many types of phenotypic …

Active DNA demethylation at enhancers during the vertebrate phylotypic period

O Bogdanović, AH Smits, E de la Calle Mustienes… - Nature …, 2016 - nature.com
The vertebrate body plan and organs are shaped during a conserved embryonic phase
called the phylotypic stage. However, the mechanisms that guide the epigenome through …

Hypoxia causes transgenerational impairments in reproduction of fish

SY Wang, K Lau, KP Lai, JW Zhang, ACK Tse… - Nature …, 2016 - nature.com
Hypoxia is amongst the most widespread and pressing problems in aquatic environments.
Here we demonstrate that fish (Oryzias melastigma) exposed to hypoxia show reproductive …

Bisphenol A causes reproductive toxicity, decreases dnmt1 transcription, and reduces global DNA methylation in breeding zebrafish (Danio rerio)

LV Laing, J Viana, EL Dempster, M Trznadel… - Epigenetics, 2016 - Taylor & Francis
Bisphenol A (BPA) is a commercially important high production chemical widely used in
epoxy resins and polycarbonate plastics, and is ubiquitous in the environment. Previous …

Loss of 5-hydroxymethylcytosine is linked to gene body hypermethylation in kidney cancer

K Chen, J Zhang, Z Guo, Q Ma, Z Xu, Y Zhou, Z Xu, Z Li… - Cell research, 2016 - nature.com
Abstract Both 5-methylcytosine (5mC) and its oxidized form 5-hydroxymethylcytosine
(5hmC) have been proposed to be involved in tumorigenesis. Because the readout of the …

The role of non-genetic inheritance in evolutionary rescue: epigenetic buffering, heritable bet hedging and epigenetic traps

RE O'Dea, DWA Noble, SL Johnson… - Environmental …, 2016 - academic.oup.com
Rapid environmental change is predicted to compromise population survival, and the
resulting strong selective pressure can erode genetic variation, making evolutionary rescue …

Transgenerational plasticity and environmental stress: do paternal effects act as a conduit or a buffer?

AS Guillaume, K Monro, DJ Marshall - Functional Ecology, 2016 - Wiley Online Library
For most organisms, early life‐history stages are the most sensitive to environmental stress
and so transgenerational phenotypic plasticity, whereby the parental environment and …

Both diet and gene mutation induced obesity affect oocyte quality in mice

YJ Hou, CC Zhu, X Duan, HL Liu, Q Wang, SC Sun - Scientific reports, 2016 - nature.com
Obesity was shown to cause reproductive dysfunctions such as reduced conception,
infertility and early pregnancy loss. However, the possible effects of obesity on oocyte quality …

Evolutionary transition of promoter and gene body DNA methylation across invertebrate–vertebrate boundary

TE Keller, P Han, SV Yi - Molecular biology and evolution, 2016 - academic.oup.com
Genomes of invertebrates and vertebrates exhibit highly divergent patterns of DNA
methylation. Invertebrate genomes tend to be sparsely methylated, and DNA methylation is …