Epigenetics and inheritance of phenotype variation in livestock
KA Triantaphyllopoulos, I Ikonomopoulos… - Epigenetics & …, 2016 - Springer
Epigenetic inheritance plays a crucial role in many biological processes, such as gene
expression in early embryo development, imprinting and the silencing of transposons. It has …
expression in early embryo development, imprinting and the silencing of transposons. It has …
Epigenomics in marine fishes
DCH Metzger, PM Schulte - Marine Genomics, 2016 - Elsevier
Epigenetic mechanisms are an underappreciated and often ignored component of an
organism's response to environmental change and may underlie many types of phenotypic …
organism's response to environmental change and may underlie many types of phenotypic …
Active DNA demethylation at enhancers during the vertebrate phylotypic period
O Bogdanović, AH Smits, E de la Calle Mustienes… - Nature …, 2016 - nature.com
The vertebrate body plan and organs are shaped during a conserved embryonic phase
called the phylotypic stage. However, the mechanisms that guide the epigenome through …
called the phylotypic stage. However, the mechanisms that guide the epigenome through …
Hypoxia causes transgenerational impairments in reproduction of fish
Hypoxia is amongst the most widespread and pressing problems in aquatic environments.
Here we demonstrate that fish (Oryzias melastigma) exposed to hypoxia show reproductive …
Here we demonstrate that fish (Oryzias melastigma) exposed to hypoxia show reproductive …
Bisphenol A causes reproductive toxicity, decreases dnmt1 transcription, and reduces global DNA methylation in breeding zebrafish (Danio rerio)
LV Laing, J Viana, EL Dempster, M Trznadel… - Epigenetics, 2016 - Taylor & Francis
Bisphenol A (BPA) is a commercially important high production chemical widely used in
epoxy resins and polycarbonate plastics, and is ubiquitous in the environment. Previous …
epoxy resins and polycarbonate plastics, and is ubiquitous in the environment. Previous …
Loss of 5-hydroxymethylcytosine is linked to gene body hypermethylation in kidney cancer
Abstract Both 5-methylcytosine (5mC) and its oxidized form 5-hydroxymethylcytosine
(5hmC) have been proposed to be involved in tumorigenesis. Because the readout of the …
(5hmC) have been proposed to be involved in tumorigenesis. Because the readout of the …
The role of non-genetic inheritance in evolutionary rescue: epigenetic buffering, heritable bet hedging and epigenetic traps
Rapid environmental change is predicted to compromise population survival, and the
resulting strong selective pressure can erode genetic variation, making evolutionary rescue …
resulting strong selective pressure can erode genetic variation, making evolutionary rescue …
Transgenerational plasticity and environmental stress: do paternal effects act as a conduit or a buffer?
For most organisms, early life‐history stages are the most sensitive to environmental stress
and so transgenerational phenotypic plasticity, whereby the parental environment and …
and so transgenerational phenotypic plasticity, whereby the parental environment and …
Both diet and gene mutation induced obesity affect oocyte quality in mice
YJ Hou, CC Zhu, X Duan, HL Liu, Q Wang, SC Sun - Scientific reports, 2016 - nature.com
Obesity was shown to cause reproductive dysfunctions such as reduced conception,
infertility and early pregnancy loss. However, the possible effects of obesity on oocyte quality …
infertility and early pregnancy loss. However, the possible effects of obesity on oocyte quality …
Evolutionary transition of promoter and gene body DNA methylation across invertebrate–vertebrate boundary
Genomes of invertebrates and vertebrates exhibit highly divergent patterns of DNA
methylation. Invertebrate genomes tend to be sparsely methylated, and DNA methylation is …
methylation. Invertebrate genomes tend to be sparsely methylated, and DNA methylation is …