Transforms and operators for directional bioimage analysis: a survey

Z Püspöki, M Storath, D Sage, M Unser - Focus on bio-image informatics, 2016 - Springer
We give a methodology-oriented perspective on directional image analysis and rotation-
invariant processing. We review the state of the art in the field and make connections with …

Multi-scale modeling of the cardiovascular system: disease development, progression, and clinical intervention

Y Zhang, VH Barocas, SA Berceli, CE Clancy… - Annals of biomedical …, 2016 - Springer
Cardiovascular diseases (CVDs) are the leading cause of death in the western world. With
the current development of clinical diagnostics to more accurately measure the extent and …

Self‐assembled wound dressings silence MMP‐9 and improve diabetic wound healing in vivo

SA Castleberry, BD Almquist, W Li, T Reis… - Advanced …, 2016 - Wiley Online Library
DOI: 10.1002/adma. 201503565 granulation tissue, the early connective tissue that fills a
wound, as well as inactivates important growth factors that are critical to the process of …

Actomyosin dynamics drive local membrane component organization in an in vitro active composite layer

DV Köster, K Husain, E Iljazi, A Bhat… - Proceedings of the …, 2016 - National Acad Sciences
The surface of a living cell provides a platform for receptor signaling, protein sorting,
transport, and endocytosis, whose regulation requires the local control of membrane …

[HTML][HTML] Increased peri-ductal collagen micro-organization may contribute to raised mammographic density

JC McConnell, OV O'Connell, K Brennan… - Breast Cancer …, 2016 - Springer
Background High mammographic density is a therapeutically modifiable risk factor for breast
cancer. Although mammographic density is correlated with the relative abundance of …

[HTML][HTML] Tensile forces originating from cancer spheroids facilitate tumor invasion

KS Kopanska, Y Alcheikh, R Staneva, D Vignjevic… - PloS one, 2016 - journals.plos.org
The mechanical properties of tumors and the tumor environment provide important
information for the progression and characterization of cancer. Tumors are surrounded by an …

A human in vitro model of Duchenne muscular dystrophy muscle formation and contractility

AP Nesmith, MA Wagner, FS Pasqualini… - Journal of Cell …, 2016 - rupress.org
Tongue weakness, like all weakness in Duchenne muscular dystrophy (DMD), occurs as a
result of contraction-induced muscle damage and deficient muscular repair. Although …

A validated software application to measure fiber organization in soft tissue

EE Morrill, AN Tulepbergenov, CJ Stender… - … and modeling in …, 2016 - Springer
The mechanical behavior of soft connective tissue is governed by a dense network of fibrillar
proteins in the extracellular matrix. Characterization of this fibrous network requires the …

Spatiotemporal control of cardiac anisotropy using dynamic nanotopographic cues

PY Mengsteab, K Uto, AST Smith, S Frankel, E Fisher… - Biomaterials, 2016 - Elsevier
Coordinated extracellular matrix spatiotemporal reorganization helps regulate cellular
differentiation, maturation, and function in vivo, and is therefore vital for the correct formation …

[HTML][HTML] Sensing surface mechanical deformation using active probes driven by motor proteins

D Inoue, T Nitta, AMR Kabir, K Sada, JP Gong… - Nature …, 2016 - nature.com
Studying mechanical deformation at the surface of soft materials has been challenging due
to the difficulty in separating surface deformation from the bulk elasticity of the materials …