Exogenous melatonin has been investigated as treatment for a number of medical and
surgical diseases, demonstrating encouraging results. The aim of this review was to present …

Background The introduction of proton pump inhibitors (PPIs) into clinical practice has
revolutionized the management of acid-related diseases. Studies in primary care and …

Background Low-dose aspirin has proven effectiveness in secondary and primary
prevention of cardiovascular events, but is also associated with an increased risk of major …

Objective To evaluate gastrointestinal (GI) perforation in rheumatoid arthritis (RA) patients
receiving tofacitinib, tocilizumab, or other biologic agents. Methods Using health plan data …

Non-steroidal anti-inflammatory drug (NSAID) use increases the risk of gastrointestinal
complications such as ulcers or bleeding. The presence of factors like advanced age, history …

Background & Aims It is not clear whether use of low-dose aspirin should be resumed after
an episode of lower gastrointestinal (GI) bleeding. We assessed the long-term risks of …

Gastrointestinal bleeding (GIB) is a serious, potentially life-threatening disease that leads to
almost 1 million hospitalizations annually in the United States. 1, 2 Because this is a …

Proton pump inhibitors (PPIs) represent a milestone in the treatment of acid-related
diseases, and are the mainstay in preventing upper gastrointestinal bleeding in high-risk …

The goal for this study was to evaluate safety regarding anticoagulant activity and platelet
activation during daily consumption of an aqueous cyanophyta extract (ACE), containing a …

AIM To assess the prevalence of possible risk factors of upper gastrointestinal bleeding
(UGIB) and their age-group specific trend among the general population and osteoarthritis …