[HTML][HTML] DLC1 is the principal biologically-relevant down-regulated DLC family member in several cancers
D Wang, X Qian, M Rajaram, ME Durkin, DR Lowy - Oncotarget, 2016 - ncbi.nlm.nih.gov
The RHO family of RAS-related GTPases in tumors may be activated by reduced levels of
RHO GTPase accelerating proteins (GAPs). One common mechanism is decreased …
RHO GTPase accelerating proteins (GAPs). One common mechanism is decreased …
Dlc1 interaction with non-muscle myosin heavy chain II-A (Myh9) and Rac1 activation
MG Sabbir, R Dillon, MRA Mowat - Biology open, 2016 - journals.biologists.com
The Deleted in liver cancer 1 (Dlc1) gene codes for a Rho GTPase-activating protein that
also acts as a tumour suppressor gene. Several studies have consistently found that …
also acts as a tumour suppressor gene. Several studies have consistently found that …
Aberrant DNA methylation of alternative promoter of DLC1 isoform 1 in meningiomas
M Bujko, P Kober, N Rusetska, M Wakuła… - Journal of Neuro …, 2016 - Springer
DLC1 encodes GTPase-activating protein with a well-documented tumor suppressor activity.
This gene is downregulated in various tumors through aberrant promoter hypermethylation …
This gene is downregulated in various tumors through aberrant promoter hypermethylation …
The Role of Chromosomal Instability and Epigenetics in Colorectal Cancers Lacking β‐Catenin/TCF Regulated Transcription
WM Abdel-Rahman, JE Lotsari-Salomaa… - Gastroenterology …, 2016 - Wiley Online Library
All colorectal cancer cell lines except RKO displayed active β‐catenin/TCF regulated
transcription. This feature of RKO was noted in familial colon cancers; hence our aim was to …
transcription. This feature of RKO was noted in familial colon cancers; hence our aim was to …
[HTML][HTML] The nuclear corepressor 1 and the thyroid hormone receptor β suppress breast tumor lymphangiogenesis
O Martínez-Iglesias, D Olmeda, E Alonso-Merino… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Abstract Vascular Endotelial Growth Factors C and D (VEGF-C and VEGF-D) are crucial
regulators of lymphangiogenesis, a main event in the metastatic spread of breast cancer …
regulators of lymphangiogenesis, a main event in the metastatic spread of breast cancer …
Transcriptomic analysis reveals sex-specific differences in the expression of Dcl1 and Fis1 genes in the radio-adaptive response of thymocytes to TRP53-mediated …
P López-Nieva, M Malavé, L González-Sánchez… - BMC genomics, 2016 - Springer
Abstract Background Radio-Adaptive Response (RAR) is a biological defense mechanism
whereby exposure to low dose ionizing radiation (IR) mitigates the detrimental effects of high …
whereby exposure to low dose ionizing radiation (IR) mitigates the detrimental effects of high …
[PDF][PDF] Research Article The Role of Chromosomal Instability and Epigenetics in Colorectal Cancers Lacking 𝛽-Catenin/TCF Regulated Transcription
WM Abdel-Rahman, JE Lotsari-Salomaa, S Kaur… - 2016 - academia.edu
All colorectal cancer cell lines except RKO displayed active 𝛽-catenin/TCF regulated
transcription. This feature of RKO was noted in familial colon cancers; hence our aim was to …
transcription. This feature of RKO was noted in familial colon cancers; hence our aim was to …