Emerging role of microRNA-21 in cancer
YH Feng, CJ Tsao - Biomedical reports, 2016 - spandidos-publications.com
MicroRNAs (miRs) are a class of single-stranded RNA molecules of 15-27 nucleotides in
length that regulate gene expression at the post-translational level. miR-21 is one of the …
length that regulate gene expression at the post-translational level. miR-21 is one of the …
Biogenesis and regulation of the let-7 miRNAs and their functional implications
H Lee, S Han, CS Kwon, D Lee - Protein & cell, 2016 - academic.oup.com
The let-7 miRNA was one of the first miRNAs discovered in the nematode, Caenorhabditis
elegans, and its biological functions show a high level of evolutionary conservation from the …
elegans, and its biological functions show a high level of evolutionary conservation from the …
Distribution of miRNA expression across human tissues
We present a human miRNA tissue atlas by determining the abundance of 1997 miRNAs in
61 tissue biopsies of different organs from two individuals collected post-mortem. One …
61 tissue biopsies of different organs from two individuals collected post-mortem. One …
miRTarBase 2016: updates to the experimentally validated miRNA-target interactions database
MicroRNAs (miRNAs) are small non-coding RNAs of approximately 22 nucleotides, which
negatively regulate the gene expression at the post-transcriptional level. This study …
negatively regulate the gene expression at the post-transcriptional level. This study …
The human epididymis: its function in sperm maturation
R Sullivan, R Mieusset - Human reproduction update, 2016 - academic.oup.com
BACKGROUND Spermatozoa acquire their fertilizing ability and forward motility properties
during epididymal transit. Our knowledge of gamete physiology is based on studies …
during epididymal transit. Our knowledge of gamete physiology is based on studies …
Single-cell sequencing of the small-RNA transcriptome
OR Faridani, I Abdullayev, M Hagemann-Jensen… - Nature …, 2016 - nature.com
Little is known about the heterogeneity of small-RNA expression as small-RNA profiling has
so far required large numbers of cells. Here we present a single-cell method for small-RNA …
so far required large numbers of cells. Here we present a single-cell method for small-RNA …
The role of miR-126 in embryonic angiogenesis, adult vascular homeostasis, and vascular repair and its alterations in atherosclerotic disease
DA Chistiakov, AN Orekhov, YV Bobryshev - Journal of molecular and …, 2016 - Elsevier
Abstract Expression of microRNA (miR)-126 is enriched in endothelial cells (ECs) and
endothelial progenitor cells (EPCs). MiR-126 is considered a master regulator of …
endothelial progenitor cells (EPCs). MiR-126 is considered a master regulator of …
Kidney biomarkers in cirrhosis
C Francoz, MK Nadim, F Durand - Journal of hepatology, 2016 - Elsevier
Impaired renal function due to acute kidney injury (AKI) and/or chronic kidney diseases
(CKD) is frequent in cirrhosis. Recurrent episodes of AKI may occur in end-stage cirrhosis …
(CKD) is frequent in cirrhosis. Recurrent episodes of AKI may occur in end-stage cirrhosis …
[HTML][HTML] Fetal bovine serum RNA interferes with the cell culture derived extracellular RNA
Fetal bovine serum (FBS) has been used in eukaryotic cell cultures for decades. However,
little attention has been paid to the biological effects associated with RNA content of FBS on …
little attention has been paid to the biological effects associated with RNA content of FBS on …
Extracellular miRNA: a collision of two paradigms
A Turchinovich, AG Tonevitsky, B Burwinkel - Trends in Biochemical …, 2016 - cell.com
Since their discovery in 2008, extracellular miRNAs (ex-miRNAs) have persisted as one of
the major themes of molecular and cellular biology. The main reason for this remarkable …
the major themes of molecular and cellular biology. The main reason for this remarkable …