Research into biomarkers of periodontitis is driven by mainly three targets: to identify 'at
risk'patients before periodontal tissue destruction occurs; to determine disease activity and …

Saliva contains a variety of biomolecules, including DNA, coding and noncoding RNA,
proteins, metabolites and microbiota. The changes in the salivary levels of these molecular …

Novel biomarkers and non-invasive diagnostic methods are urgently needed for the
screening of gastric cancer to reduce its high mortality. We employed quantitative …

Objectives Saliva is a biological fluid suitable for biomarker analysis, and differences in the
salivary microbiota in oral health and disease have been reported. For such comparative …

Background Of all human oral carcinomas, 41% are localized to the tongue. Despite
considerable improvements in both diagnosis and treatment, tongue squamous cell …

Extracellular vesicles (EVs) are membrane surrounded structures released by cells, which
have been increasingly recognized as mediators of intercellular communication. Recent …

Salivary diagnostics is a rapidly advancing field that offers clinicians and patients the
potential of rapid, noninvasive diagnostics with excellent accuracy. In order for the complete …

Background To examine the roles of long noncoding RNAs (lncRNAs) in the regulation of
primary Sjögren's syndrome (pSS) and reveal the expression profile of lncRNAs in labial …

Primary SS (pSS) is characterized by chronic dysfunction and destruction of exocrine
glands, in particular the salivary and lacrimal glands, leading to persistent dryness of the …

Saliva provides a valuable tool for assessing oral and systemic diseases, but concentrations
of salivary components are very small, calling the need for precise analysis methods. In this …