Meta-analysis reveals PTPN22 1858C/T polymorphism confers susceptibility to rheumatoid arthritis in Caucasian but not in Asian population
Abstract The PTPN22 1858C/T polymorphism is associated with rheumatoid arthritis (RA).
However, reports from the Asian populations are conflicting in nature and lacks consensus …
However, reports from the Asian populations are conflicting in nature and lacks consensus …
PTPN22 polymorphisms, but not R620W, were associated with the genetic susceptibility of systemic lupus erythematosus and rheumatoid arthritis in a Chinese Han …
L Tang, Y Wang, S Zheng, M Bao, Q Zhang, J Li - Human Immunology, 2016 - Elsevier
Objectives The present study aimed to detect a possible association between PTPN22 gene
polymorphisms and rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) in a …
polymorphisms and rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) in a …
Distribution of PTPN22 polymorphisms in SLE from western Mexico: correlation with mRNA expression and disease activity
Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune inflammatory disease
characterized by loss of self-tolerance with hyperactivation of autoreactive T and B cells …
characterized by loss of self-tolerance with hyperactivation of autoreactive T and B cells …
Association of juvenile idiopathic arthritis with PTPN22 rs2476601 is specific to females in a Greek population
GN Goulielmos, RC Chiaroni-Clarke… - Pediatric …, 2016 - Springer
Background Juvenile idiopathic arthritis (JIA) is an autoimmune disease characterized by
persistent chronic arthritis. Disease risk is believed to be influenced by both genetic and …
persistent chronic arthritis. Disease risk is believed to be influenced by both genetic and …
Genotype-phenotype associations of the CD-associated single nucleotide polymorphism within the gene locus encoding protein tyrosine phosphatase non-receptor …
MR Spalinger, J Zeitz, L Biedermann, JB Rossel… - PloS one, 2016 - journals.plos.org
Background Protein tyrosine phosphatase non-receptor type 22 (PTPN22) plays an
important role in immune cell function and intestinal homeostasis. The single nucleotide …
important role in immune cell function and intestinal homeostasis. The single nucleotide …
[PDF][PDF] Multiple Autoimmune Syndrome-Clinical, immunological and genotypic characterization of a group of patients from Unidade de Imunologia Clínica-Centro …
MB Fidalgo - 2016 - repositorio-aberto.up.pt
Autoimmune diseases (AIDs) are complex, chronic diseases due to the loss of
immunological tolerance to self-antigens.[1-12] AIDs are a heterogeneous group, comprised …
immunological tolerance to self-antigens.[1-12] AIDs are a heterogeneous group, comprised …
[PDF][PDF] MAPPING THE GENETIC DETERMINANTS OF IMMUNE DISEASE SUSCEPTIBILITY
S Kariuki - 2016 - knowledge.uchicago.edu
In this dissertation, I focus on mapping intermediate phenotypes, or endophenotypes, to
characterize the molecular basis of inter-individual variation in immune disease …
characterize the molecular basis of inter-individual variation in immune disease …