Fatty acids, eicosanoids and PPAR gamma

R Marion-Letellier, G Savoye, S Ghosh - European journal of pharmacology, 2016 - Elsevier
Peroxisome proliferator-activated receptor γ (PPARγ) belongs to the family of nuclear
nuclear receptors and is mainly expressed in adipose tissue, hematopoietic cells and the …

[HTML][HTML] PPARγ as a therapeutic target to rescue mitochondrial function in neurological disease

JC Corona, MR Duchen - Free Radical Biology and Medicine, 2016 - Elsevier
There is increasing evidence for the involvement of mitochondrial dysfunction and oxidative
stress in the pathogenesis of many of the major neurodegenerative and neuroinflammatory …

Long-chain polyunsaturated fatty acids regulation of PPARs, signaling: Relationship to tissue development and aging

F Echeverría, M Ortiz, R Valenzuela… - … Leukotrienes and Essential …, 2016 - Elsevier
Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors that function as
ligand-dependent transcription factors that can be activated by different types of fatty acids …

Modulation of inflammation and immunity by dietary conjugated linoleic acid

M Viladomiu, R Hontecillas… - European journal of …, 2016 - Elsevier
Conjugated linoleic acid (CLA) is a mixture of positional and geometric isomers of linoleic
acid. This family of polyunsaturated fatty acids has drawn significant attention in the last …

Transcriptional control of physiological and pathological processes by the nuclear receptor PPARβ/δ

NS Tan, M Vázquez-Carrera, A Montagner… - Progress in Lipid …, 2016 - Elsevier
Peroxisome proliferator-activated receptors (PPARs) are a class of transcription factors that
belong to the nuclear hormone receptor superfamily, and their activities are dependent on …

Modulation of PPAR expression and activity in response to polyphenolic compounds in high fat diets

JA Domínguez-Avila, GA González-Aguilar… - International journal of …, 2016 - mdpi.com
Peroxisome proliferator-activated receptors (PPAR) are transcription factors that modulate
energy metabolism in liver, adipose tissue and muscle. High fat diets (HFD) can negatively …

Antidiabetic Properties, Bioactive Constituents, and Other Therapeutic Effects of Scoparia dulcis

G Pamunuwa, DN Karunaratne… - Evidence‐Based …, 2016 - Wiley Online Library
This review discusses the antidiabetic activities of Scoparia dulcis as well as its antioxidant
and anti‐inflammatory properties in relation to the diabetes and its complications …

Differences in the skeletal muscle transcriptome profile associated with extreme values of fatty acids content

ASM Cesar, LCA Regitano, MD Poleti, SCS Andrade… - BMC genomics, 2016 - Springer
Background Lipids are a class of molecules that play an important role in cellular structure
and metabolism in all cell types. In the last few decades, it has been reported that long-chain …

Peroxisome proliferator‐activated receptors in female reproduction and fertility

M Vitti, G Di Emidio, M Di Carlo, G Carta… - PPAR …, 2016 - Wiley Online Library
Reproductive functions may be altered by the exposure to a multitude of endogenous and
exogenous agents, drug or environmental pollutants, which are known to affect gene …

PPARβ/δ and lipid metabolism in the heart

X Palomer, E Barroso, M Zarei, G Botteri… - … et Biophysica Acta (BBA …, 2016 - Elsevier
Cardiac lipid metabolism is the focus of attention due to its involvement in the development
of cardiac disorders. Both a reduction and an increase in fatty acid utilization make the heart …