[HTML][HTML] In silico Pathway Activation Network Decomposition Analysis (iPANDA) as a method for biomarker development

IV Ozerov, KV Lezhnina, E Izumchenko… - Nature …, 2016 - nature.com
Signalling pathway activation analysis is a powerful approach for extracting biologically
relevant features from large-scale transcriptomic and proteomic data. However, modern …

[HTML][HTML] Neural innervation stimulates splenic TFF2 to arrest myeloid cell expansion and cancer

Z Dubeykovskaya, Y Si, X Chen, DL Worthley… - Nature …, 2016 - nature.com
Abstract CD11b+ Gr-1+ myeloid-derived suppressor cells (MDSCs) expand in the spleen
during cancer and promote progression through suppression of cytotoxic T cells. An anti …

[HTML][HTML] Integrated left ventricular global transcriptome and proteome profiling in human end-stage dilated cardiomyopathy

D Colak, AA Alaiya, N Kaya, NP Muiya, O AlHarazi… - PloS one, 2016 - journals.plos.org
Aims The disease pathways leading to idiopathic dilated cardiomyopathy (DCM) are still
elusive. The present study investigated integrated global transcriptional and translational …

[HTML][HTML] A comparative evaluation of data-merging and meta-analysis methods for reconstructing gene-gene interactions

V Lagani, AD Karozou, D Gomez-Cabrero… - BMC …, 2016 - Springer
Background We address the problem of integratively analyzing multiple gene expression,
microarray datasets in order to reconstruct gene-gene interaction networks. Integrating …

[HTML][HTML] Mitochondrial and oxidative stress genes are differentially expressed in neutrophils of sJIA patients treated with tocilizumab: a pilot microarray study

E Omoyinmi, R Hamaoui, A Bryant, MC Jiang… - Pediatric …, 2016 - Springer
Background Various pathways involved in the pathogenesis of sJIA have been identified
through gene expression profiling in peripheral blood mononuclear cells (PBMC), but not in …

Osteochondroreticular stem cells for bone and cartilage regeneration

TC Wang, D Worthley, S Mukherjee - 2016 - Google Patents
WO2016073989A2 - Osteochondroreticular stem cells for bone and cartilage regeneration -
Google Patents WO2016073989A2 - Osteochondroreticular stem cells for bone and …

Mining raw gene expression microarray data for analyzing synchronous and metachronous liver metastatic lesions from colorectal cancer

H Wang, X Lv - 2016 9th International Congress on Image and …, 2016 - ieeexplore.ieee.org
Gene expression microarray has become a major source for producing high-throughput
experiment data. Data mining has been widely applied to dissect the genetic basis of …

DNA probe signal processing for identification of abnormal gene regulation and pathogenetic understanding—A data mining approach

H Wang, W Cai - 2016 IEEE 13th International Conference on …, 2016 - ieeexplore.ieee.org
Gene expression microarray leverages DNA probes to acquire signal intensity in the
hybridized biological samples, and has become a major source for producing high …

[PDF][PDF] Dimensionality Reduction Methods for Microarray Cancer Data Using Prior Knowledge

ZM Hira - 2016 - core.ac.uk
Microarray studies are currently a very popular source of biological information. They allow
the simultaneous measurement of hundreds of thousands of genes, drastically increasing …

[PDF][PDF] Neural innervation stimulates splenic TFF2 to arrest myeloid cell expansion and cancer

Y Si, X Chen, DL Worthley, BW Renz, AM Urbanska… - 2016 - core.ac.uk
Results Splenic TFF2 is regulated by vagal nerve. TFF2 protein is expressed in the spleen
under normal physiological conditions (Fig. 1a). Following chemically induced colitis model …