[HTML][HTML] The multifaceted role of astrocytes in regulating myelination

H Kıray, SL Lindsay, S Hosseinzadeh… - Experimental neurology, 2016 - Elsevier
Astrocytes are the major glial cell of the central nervous system (CNS), providing both
metabolic and physical support to other neural cells. After injury, astrocytes become reactive …

Astrocytes in multiple sclerosis

SK Ludwin, VTS Rao, CS Moore… - Multiple sclerosis …, 2016 - journals.sagepub.com
Recent experimental and clinical studies on astrocytes are unraveling the capabilities of
these multi-functional cells in normal homeostasis, and in central nervous system (CNS) …

[HTML][HTML] Astrocytes in oligodendrocyte lineage development and white matter pathology

J Li, L Zhang, Y Chu, M Namaka, B Deng… - Frontiers in cellular …, 2016 - frontiersin.org
White matter is primarily composed of myelin and myelinated axons. Structural and
functional completeness of myelin is critical for the reliable and efficient transmission of …

Gene expression profiling of the astrocyte transcriptome in multiple sclerosis normal appearing white matter reveals a neuroprotective role

R Waller, MN Woodroofe, SB Wharton, PG Ince… - Journal of …, 2016 - Elsevier
Multiple sclerosis (MS) is a chronic, inflammatory, demyelinating disease of the central
nervous system (CNS). White matter lesions in MS are surrounded by areas of non …

The role of growth factors as a therapeutic approach to demyelinating disease

Y Huang, CF Dreyfus - Experimental neurology, 2016 - Elsevier
A variety of growth factors are being explored as therapeutic agents relevant to the axonal
and oligodendroglial deficits that occur as a result of demyelinating lesions such as are …

[HTML][HTML] Stem cell therapy for white matter disorders: don't forget the microenvironment!

S Dooves, MS van der Knaap, VM Heine - Journal of Inherited Metabolic …, 2016 - Springer
White matter disorders (WMDs) are a major source of handicap at all ages. They often lead
to progressive neurological dysfunction and early death. Although causes are highly …

The melanocortin ACTH 1-39 promotes protection of oligodendrocytes by astroglia

RP Lisak, L Nedelkoska, JA Benjamins - Journal of the Neurological …, 2016 - Elsevier
Damage to myelin and oligodendroglia (OL) in multiple sclerosis (MS) results from a wide
array of mechanisms including excitotoxicity, neuroinflammation and oxidative stress. We …

磁共振波谱在早产儿神经系统发育落后早期预测的价值

刘绪明, 张嫣然, 万诚, 林达, 余捷, 项剑瑜, 周露… - 医学影像学杂志, 2016 - cqvip.com
目的探讨早产儿1H-MRS 脑内代谢物与Gesell 发育商间的相关性, 为早产儿神经系统发育落后
的早期诊断及预测提供帮助. 方法对我院符合条件的45 例早产儿及30 例同期足月儿于出生后1 …

Multiple Sclerosis: Etiology and mechanism, with special reference to Asians

J Kira - Neuroimmunological Diseases, 2016 - Springer
Multiple sclerosis (MS) is a disease that targets myelin in the central nervous system (CNS).
It is thought to be an autoimmune disease but this is not yet proven. Genome-wide …

Crosstalk between cerebral endothelium and oligodendrocyte after stroke

A Shindo, T Maki, K Itoh, N Miyamoto, N Egawa… - … Mechanisms of Brain …, 2016 - Springer
It is now well-accepted that the cerebrovascular system does not merely provide inert pipes
for blood delivery to the brain. Cerebral endothelial cells may compose an embedded …