Ischemic disorders, such as myocardial infarction, stroke, and peripheral vascular disease,
are the most common causes of debilitating disease and death in westernized cultures. The …

Treatments for acute ischaemic stroke continue to evolve after the superior value of
endovascular thrombectomy was confirmed over systemic thrombolysis. Unfortunately …

Acute brain ischemia induces a local neuroinflammatory reaction and alters peripheral
immune homeostasis at the same time. Recent evidence has suggested a key role of the gut …

Over the past several decades, there have been substantial advances in our knowledge of
the pathophysiology of stroke. Understanding the benefits of timely reperfusion has led to …

Background and Purpose—Antibiotics disturbing microbiota are often used in treatment of
poststroke infections. A bidirectional brain–gut microbiota axis was recently suggested as a …

Background: Dysphagia is associated with poor outcome in stroke patients. Studies
investigating the association of dysphagia and early dysphagia screening (EDS) with …

Significance: Stroke is the leading cause of morbidity and mortality worldwide. Inflammatory
cascades have a major impact on outcome and regeneration after ischemic stroke. High …

Inflammatory mechanisms are currently considered as a prime target for stroke therapy.
There is evidence from animal studies that immune signals and mediators can have both …

Highlights•T cells serve both inflammatory and protective roles in acute stroke.•Effects are
direct and through modulation of the inflammatory milieu.•Following the early phase, there is …

The secondary neuroinflammatory response has come into focus of experimental stroke
research. Immunological mechanisms after acute stroke are being investigated in the hope …