Network biology is a rapidly developing area of biomedical research and reflects the current
view that complex phenotypes, such as disease susceptibility, are not the result of single …

The first step in the infection of humans by microbial pathogens is their adherence to host
tissue cells, which is frequently based on the binding of carbohydrate-binding proteins …

Cellular innate immunity poses the first hurdle against invading viruses in their attempt to
establish infection. This antiviral response is manifested with the detection of viral …

Cell lineages, which shape the body architecture and specify cell functions, derive from the
integration of a plethora of cell intrinsic and extrinsic signals. These signals trigger a …

Background Alterations in genetic and epigenetic landscapes are known to contribute to the
development of different types of cancer. However, the mechanistic links between …

While scientific methods have dominated research approaches in biology over the past
decades, it is increasingly recognized that the complexity of biological systems must be …

High-resolution mass spectrometry can now track all temporal changes in the
phosphoproteomes of cells. The resulting time-series datasets pose a challenge ripe for the …

In the paper we present multifocal highlighting in reverse engineered component diagrams
to support software engineers in answering questions on relations between a number of …

Biomedical research increasingly relies on the analysis and visualization of a wide range of
collected data. However, for certain research questions, such as those investigating the …