Motor units are the fundamental elements responsible for muscle movement. They are
formed by lower motor neurons and their muscle targets, synapsed via neuromuscular …

Motoneurons develop extensive dendritic trees for receiving excitatory and inhibitory
synaptic inputs to perform a variety of complex motor tasks. At birth, the somatodendritic …

Generic spinal motor neuron identity is established by cooperative binding of programming
transcription factors (TFs), Isl1 and Lhx3, to motor-neuron-specific enhancers. How …

The accuracy of neural circuit assembly relies on the precise spatial and temporal control of
synaptic specificity determinants during development. Hox transcription factors govern key …

Movement requires effective relay of commands from the CNS to muscles at neuromuscular
junctions (NMJs). To form NMJs, developing motor neuron axons exit the spinal cord and …

Abstract Glycerophosphodiester phosphodiesterase 2 (GDE2) is a six-transmembrane
protein that cleaves glycosylphosphatidylinositol (GPI) anchors to regulate GPI-anchored …

Motoneurone sind eine Schaltstelle zwischen dem Zentralnervensystem und der Muskulatur
und können die Muskelkontraktion auslösen. Motoneurone sind topologisch organisiert, dh …

El correcto ensamblaje de los circuitos neuronales formados durante el desarrollo
embrionario depende intrínsecamente de la fina regulación en la expresión de diversas …

During the past 25 years or so, the use of increasingly sophisticated genetically engineered
mutant mice, combined with innovation in the use of molecular tracers for visual detection of …