BACKGROUND Androgens, FSH, anti-Müllerian hormone (AMH) and estradiol (E2) are
essential in human ovarian folliculogenesis. However, the interactions between these four …

Steroid hormone receptors mediate numerous crucial biological processes and are
classically thought to function as transcriptional regulators in the nucleus. However, it has …

Follicle-stimulating hormone receptor (FSHR) and its intracellular signaling control
mammalian follicular development and female infertility. Our previous study showed that …

Anti-Müllerian hormone (AMH) is a member of the transforming growth factor-β superfamily
and plays a crucial role in testicular and ovarian functions. In clinical practice, AMH is used …

The mammalian ovary is a dynamic organ. The coordination of follicle recruitment, selection,
and ovulation and the timely development and regression of the corpus luteum are essential …

Cellular junctions play a critical role in structural connection and signal communication
between cells in various tissues. Although there are structural and functional varieties …

Rhythmic events in female reproductive physiology, including ovulation, are tightly
controlled by the circadian timing system. The molecular clock, a feedback loop oscillator of …

Polycystic ovary syndrome (PCOS) is a frequent endocrine disorder in women. PCOS is
associated with altered features of androgen metabolism, increased insulin resistance and …

Obesity is considered detrimental to women's reproductive health. Although most of the
attention has been focused on the effects of obesity on hypothalamic function, studies …

STUDY QUESTION Can spontaneous premature ovarian failure (POF) patients derived from
population-based biobanks reveal the association between copy number variations (CNVs) …