Inhibition of hypoxia-inducible factor 1 with acriflavine sensitizes hypoxic tumor cells to photodynamic therapy with zinc phthalocyanine-encapsulating cationic …

M Broekgaarden, R Weijer, M Krekorian… - Nano Research, 2016 - Springer
Photodynamic therapy (PDT) is a tumor treatment modality in which a tumorlocalized
photosensitizer is excited with light, which results in local production of reactive oxygen …

[HTML][HTML] Inhibition of hypoxia inducible factor 1 and topoisomerase with acriflavine sensitizes perihilar cholangiocarcinomas to photodynamic therapy

R Weijer, M Broekgaarden, M Krekorian, LK Alles… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Background: Photodynamic therapy (PDT) induces tumor cell death by oxidative stress and
hypoxia but also survival signaling through activation of hypoxia-inducible factor 1 (HIF-1) …

Intravesical and alternative bladder-preservation therapies in the management of non–muscle-invasive bladder cancer unresponsive to bacillus Calmette-Guérin

RL Steinberg, LJ Thomas, KG Nepple - Urologic Oncology: Seminars and …, 2016 - Elsevier
Abstract Intravesical Bacillus Calmette-Guérin (BCG) remains the standard of care in the
treatment of bladder carcinoma in situ and as adjuvant therapy after thorough transurethral …

Hematoporphyrin monomethyl ether combined with He–Ne laser irradiation-induced apoptosis in canine breast cancer cells through the mitochondrial pathway

H Li, J Tong, J Bao, D Tang… - Journal of Veterinary …, 2016 - synapse.koreamed.org
Hematoporphyrin monomethyl ether (HMME) combined with He-Ne laser irradiation is a
novel and promising photodynamic therapy (PDT)-induced apoptosis that can be applied in …

[图书][B] New strategies to enhance photodynamic therapy for solid tumors

M Broekgaarden - 2016 - dare.uva.nl
Photodynamic therapy (PDT) has emerged as a promising alternative to conventional
cancer therapies such as surgery, chemotherapy, and radiotherapy. PDT comprises the …

[PDF][PDF] Modulating Prostate Cancer Targeting of Protease Sensitive Photosensitizer Prodrugs by Side Chain Modifications of the Polymeric Carrier

MF Zuluaga, D Gabriel… - … Therapy and Targeted … - access.archive-ouverte.unige.ch
Prodrug designs combining macromolecular delivery systems with site-selective drug
release represent a powerful strategy to increase selectivity of cancer treatments. We have …

[PDF][PDF] Selective Photodynamic Therapy for the Treatment of Prostate Cancer through Targeting of Proteolytic Activity

MF Zuluaga, N Sekkat, N Lange - … Therapy and Targeted … - access.archive-ouverte.unige.ch
Interstitial photodynamic therapy shows potential for the treatment of localized prostate
cancer. Current limitations include lack of selective accumulation of photosensitizer in …