During malignant transformation, glycosylation is heavily altered compared with healthy
tissue due to differential expression of glycosyltransferases, glycosidases and …

Conspectus Colorectal cancer (CRC) is one of the most prevalent cancers worldwide.
Delineating biological markers (biomarkers) for early detection, when treatment is most …

Aberrant glycosylation in tumours stem from altered glycosyltransferase (GT) gene
expression but can the expression profiles of these signature genes be used to classify …

Branching morphogenesis in the mammary gland is achieved by the migration of epithelial
cells through a microenvironment consisting of stromal cells and extracellular matrix (ECM) …

Abstract The β-galactoside α2-6-sialyltransferase 1 (ST6Gal-I) is the principal
sialyltransferase responsible for the addition of α2-6-sialic acid to the termini N-glycans on …

Abstract Changes in the carbohydrate structure on the surface of tumor cells is an important
feature of cancer metastasis. The specific role of sialic acids in the glycoconjugate terminal …

Altered sialylation is closely associated with tumor progression and invasiveness. Micro‐
RNAs endogenous regulators of gene expression have been implicated in human thyroid …

The aberrant sialylation profile on the surface of leukemia cells has been recognized for its
potential diagnostic value towards assessing leukemia multidrug resistance (MDR) …

Glycosylation is one of the most important posttranslational modifications of proteins and
lipids that contributes to the structural diversity of cellular molecules. Enzymes of the …

In this work, a novel label-free biosensor was designed for the sensitive and selective
determination of Neu5Acα (2-6) Gal β MP Glycoside using AuPt–PPy (polypyrrole) …