Pseudomonas aeruginosa populations undergo a characteristic evolutionary adaptation
during chronic infection of the cystic fibrosis (CF) lung, including reduced production of …

Biofilms are a major form of microbial life in which cells form dense surface associated
communities that can persist for many generations. The long-life of biofilm communities …

Pseudomonas aeruginosa is a leading cause of hospital-acquired pneumonia and chronic
lung infections in cystic fibrosis patients. Iron is essential for bacterial growth, and P …

Antimicrobial peptides (AMPs) are potent antibiotics of the innate immune system that have
been extensively investigated as a potential solution to the global problem of infectious …

Temperate phages drive genomic diversification in bacterial pathogens. Phage-derived
sequences are more common in pathogenic than nonpathogenic taxa and are associated …

Levofloxacin (LV) is a hydrophilic broad-spectrum antibiotic commonly used in pulmonary
treatment against recurrent infections of Pseudomonas aeruginosa, and particularly in cystic …

While considerable research has focused on the properties of individual bacteria, relatively
little is known about how microbial interspecies interactions alter bacterial behaviors and …

Recent years have seen renewed interest in phage therapy–the use of viruses to specifically
kill disease‐causing bacteria–because of the alarming rise in antibiotic resistance. However …

Nutritional cues differentially influence the activities of the three quorum sensing (QS)
circuits—Las, Rhl, and Pqs—in the pathogen Pseudomonas aeruginosa. A full …

Accurate typing methods are required for efficient infection control. The emergence of whole-
genome sequencing (WGS) technologies has enabled the development of genome-based …