Recent developments in the experimental investigations of relaxations in pharmaceuticals by dielectric techniques at ambient and elevated pressure
In recent years, there is a growing interest in improving the physicochemical stability of
amorphous pharmaceutical solids due to their very promising applications to manufacture …
amorphous pharmaceutical solids due to their very promising applications to manufacture …
Preparation and characterization of spray-dried co-amorphous drug–amino acid salts
KT Jensen, LI Blaabjerg, E Lenz, A Bohr… - Journal of Pharmacy …, 2016 - academic.oup.com
Objectives Recently, co-amorphous drug–amino acid mixtures were introduced as a
promising alternative to other amorphous stabilization approaches such as the use of …
promising alternative to other amorphous stabilization approaches such as the use of …
Influence of polymer molecular weight on in vitro dissolution behavior and in vivo performance of celecoxib: PVP amorphous solid dispersions
In this study, the influence of the molecular weight of polyvinylpyrrolidone (PVP) on the non-
sink in vitro dissolution and in vivo performance of celecoxib (CCX): PVP amorphous solid …
sink in vitro dissolution and in vivo performance of celecoxib (CCX): PVP amorphous solid …
Influence of PVP/VA copolymer composition on drug–polymer solubility
In this study, the influence of copolymer composition on drug–polymer solubility was
investigated. The solubility of the model drug celecoxib (CCX) in various …
investigated. The solubility of the model drug celecoxib (CCX) in various …
Effect of polymer type and drug dose on the in vitro and in vivo behavior of amorphous solid dispersions
MM Knopp, N Chourak, F Khan, J Wendelboe… - European journal of …, 2016 - Elsevier
This study investigated the non-sink in vitro dissolution behavior and in vivo performance in
rats of celecoxib (CCX) amorphous solid dispersions with polyvinyl acetate (PVA) …
rats of celecoxib (CCX) amorphous solid dispersions with polyvinyl acetate (PVA) …
Physicochemical and pharmacokinetic characterization of amorphous solid dispersion of meloxicam with enhanced dissolution property and storage stability
M Ochi, K Kimura, A Kanda, T Kawachi, A Matsuda… - AAPS …, 2016 - Springer
The aim of the present study was to develop amorphous solid dispersion (ASD) of
meloxicam (MEL) for providing rapid onset of action. ASDs of MEL with polyvinylpyrrolidone …
meloxicam (MEL) for providing rapid onset of action. ASDs of MEL with polyvinylpyrrolidone …
Application of broadband dielectric spectroscopy to study molecular mobility in pharmaceutical systems
K Grzybowska, K Adrjanowicz… - Disordered …, 2016 - Wiley Online Library
Broadband dielectric spectroscopy (BDS) is a very useful method for investigating the
molecular dynamics of various materials because it enables monitoring the molecular …
molecular dynamics of various materials because it enables monitoring the molecular …
[HTML][HTML] Thermodynamically controlled crystallization of glucose pentaacetates from amorphous phase
The α and β glucose pentaacetates are known sugar derivatives, which can be potentially
used as stabilizers of amorphous phase of active ingredients of drugs (API). In the present …
used as stabilizers of amorphous phase of active ingredients of drugs (API). In the present …
[PDF][PDF] Development of predictive tools for amorphous solid dosage forms
MM Knopp - 2016 - openscience.ub.uni-mainz.de
Background Since the introduction of modern medicine in the 19 th century, oral delivery has
remained the preferred route for drug administration due to increased patient safety and …
remained the preferred route for drug administration due to increased patient safety and …