[HTML][HTML] 4-Methylumbelliferone diminishes catabolically activated articular chondrocytes and cartilage explants via a mechanism independent of hyaluronan inhibition

S Ishizuka, EB Askew, N Ishizuka, CB Knudson… - Journal of Biological …, 2016 - ASBMB
Depletion of the cartilage proteoglycan aggrecan is one of the earliest events that occurs in
association with osteoarthritis. This loss is often accompanied by a coordinate loss in …

Metastasis-associated protein 1 (MTA1) signaling in rheumatoid synovium: regulation of inflammatory response and cytokine-mediated production of prostaglandin E2 …

H Wang, B Dong, Z Zheng, Z Wu, W Li, J Ding - … and Biophysical Research …, 2016 - Elsevier
Abnormal perpetual inflammatory response and sequential cytokine-induced prostaglandin
E 2 (PGE 2) play important roles in the pathogenesis of rheumatoid arthritis (RA). The …