Integration of optogenetics with complementary methodologies in systems neuroscience

CK Kim, A Adhikari, K Deisseroth - Nature Reviews Neuroscience, 2017 - nature.com
Modern optogenetics can be tuned to evoke activity that corresponds to naturally occurring
local or global activity in timing, magnitude or individual-cell patterning. This outcome has …

Next-generation probes, particles, and proteins for neural interfacing

J Rivnay, H Wang, L Fenno, K Deisseroth… - Science …, 2017 - science.org
Bidirectional interfacing with the nervous system enables neuroscience research, diagnosis,
and therapy. This two-way communication allows us to monitor the state of the brain and its …

In vivo imaging of neural activity

W Yang, R Yuste - Nature methods, 2017 - nature.com
Since the introduction of calcium imaging to monitor neuronal activity with single-cell
resolution, optical imaging methods have revolutionized neuroscience by enabling …

Architecture, function, and assembly of the mouse visual system

TA Seabrook, TJ Burbridge, MC Crair… - Annual review of …, 2017 - annualreviews.org
Vision is the sense humans rely on most to navigate the world, make decisions, and perform
complex tasks. Understanding how humans see thus represents one of the most …

Pan-neuronal calcium imaging with cellular resolution in freely swimming zebrafish

DH Kim, J Kim, JC Marques, A Grama… - Nature …, 2017 - nature.com
Calcium imaging with cellular resolution typically requires an animal to be tethered under a
microscope, which substantially restricts the range of behaviors that can be studied. To …

Functional and oxygen-metabolic photoacoustic microscopy of the awake mouse brain

R Cao, J Li, B Ning, N Sun, T Wang, Z Zuo, S Hu - Neuroimage, 2017 - Elsevier
A long-standing challenge in optical neuroimaging has been the assessment of
hemodynamics and oxygen metabolism in the awake rodent brain at the microscopic level …

[HTML][HTML] Frequency selection rule for high definition and high frame rate Lissajous scanning

K Hwang, YH Seo, J Ahn, P Kim, KH Jeong - Scientific reports, 2017 - nature.com
Lissajous microscanners are very attractive in compact laser scanning applications such as
endomicroscopy or pro-projection display owing to high mechanical stability and low …

[HTML][HTML] Pushing the boundaries of neuroimaging with optoacoustics

SV Ovsepian, I Olefir, G Westmeyer, D Razansky… - Neuron, 2017 - cell.com
With the central ability to visualize a variety of endogenous chromophores and biomarkers
or exogenous contrast agents, optoacoustic (photoacoustic) imaging empowers new …

[HTML][HTML] Magnetic eye tracking in mice

HL Payne, JL Raymond - elife, 2017 - elifesciences.org
Eye movements provide insights about a wide range of brain functions, from sensorimotor
integration to cognition; hence, the measurement of eye movements is an important tool in …

Imaging the pharmacology of nanomaterials by intravital microscopy: Toward understanding their biological behavior

MA Miller, R Weissleder - Advanced drug delivery reviews, 2017 - Elsevier
Therapeutic nanoparticles (NPs) can deliver cytotoxic chemotherapeutics and other drugs
more safely and efficiently to patients; furthermore, selective delivery to target tissues can …