Self-assembled cationic amphiphiles as antimicrobial peptides mimics: role of hydrophobicity, linkage type, and assembly state

Y Zhang, A Algburi, N Wang, V Kholodovych… - … , Biology and Medicine, 2017 - Elsevier
Inspired by high promise using naturally occurring antimicrobial peptides (AMPs) to treat
infections caused by antimicrobial-resistant bacteria, cationic amphiphiles (CAms) were …

Antimicrobial peptide–polymer conjugates with high activity: Influence of polymer molecular weight and peptide sequence on antimicrobial activity, proteolysis, and …

P Kumar, A Takayesu, U Abbasi… - … applied materials & …, 2017 - ACS Publications
We report the synthesis, characterization, activity, and biocompatibility of a novel series of
antimicrobial peptide–polymer conjugates. Using parent peptide aurein 2.2, we designed a …

[HTML][HTML] Assessment of antimicrobial and wound healing effects of Brevinin-2Ta against the bacterium Klebsiella pneumoniae in dermally-wounded rats

S Liu, Q Long, Y Xu, J Wang, Z Xu, L Wang, M Zhou… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Antimicrobial peptides (AMPs) are regarded as promising alternatives for antibiotics due to
their inherent capacity to prevent microbial drug resistance. Amphibians are rich source of …

Modeling diversity in structures of bacterial outer membrane lipids

H Ma, DD Cummins, NB Edelstein… - Journal of chemical …, 2017 - ACS Publications
Lipopolysaccharides (LPSs) are vital components of the outer membrane of Gram-negative
bacteria, and they act as extremely strong stimulators of innate immunity in diverse …

Protein-only, antimicrobial peptide-containing recombinant nanoparticles with inherent built-in antibacterial activity

N Serna, L Sánchez-García, A Sánchez-Chardi… - Acta biomaterialia, 2017 - Elsevier
The emergence of bacterial antibiotic resistances is a serious concern in human and animal
health. In this context, naturally occurring cationic antimicrobial peptides (AMPs) might play …

Hydrogel degradation triggered by pH for the smart release of antibiotics to combat bacterial infection

Z Lu, J Zhang, Z Yu, Q Liu, K Liu, M Li… - New Journal of …, 2017 - pubs.rsc.org
Hydrogel degradation triggered by pH for the smart release of antibiotics to combat bacterial
infection - New Journal of Chemistry (RSC Publishing) DOI:10.1039/C6NJ03260E Royal …

[HTML][HTML] Epinecidin-1 protects mice from LPS-induced endotoxemia and cecal ligation and puncture-induced polymicrobial sepsis

BC Su, HN Huang, TW Lin, CD Hsiao… - Biochimica et Biophysica …, 2017 - Elsevier
Abstract The antimicrobial peptide, epinecidin-1 (Epi), was identified from Epinephelus
coioides and may have clinical application for treating sepsis. Epi has been shown to …

Poly (amino acid-hydroxyethyl methacrylate) s with chiral lysine and/or leucine side moieties and their antibacterial abilities for biomedical applications

S Hu, W Hu, Z Li, L Ren, Y Zhao, X Yuan - Materials Science and …, 2017 - Elsevier
Biomedical applications of the synthetic polymers with amino acid side moieties have been
studied in light of their biocompatibility. In this work, poly (amino acid-hydroxyethyl …

A molecular dynamics study of the short-helical-cytolytic peptide assembling and bioactive on membrane interface

F Sun, X Ding, L Xu, JF Liang, L Chen… - The Journal of Physical …, 2017 - ACS Publications
Cytolytic peptides (CPs) have long been employed as broad-spectrum antibiotic agents to
overcome multidrug resistance. However, the development of novel peptide drugs is still …

Bioactivity and molecular characterization of bombolitins from Bombus ardens, B. consobrinus, B. terrestris and B. ussurensis

KA Yoon, YH Park, YH Koh, SH Lee - Journal of Asia-Pacific Entomology, 2017 - Elsevier
Biological activities of bombolitins from Bombus ardens, B. consobrinus, B. terrestris and B.
ussurensis (bombolitins A, C, T and U, respectively) were examined using hemolytic, anti …