Survival rates for patients with medulloblastoma have improved in the last decades but for
those who relapse outcome is dismal and new approaches are needed. Emerging drugs …

Background: Researchers report difficulties in conducting research with children and young
people with life-limiting conditions or life-threatening illnesses and their families …

Background Children with high‐risk medulloblastoma historically have had a poor
prognosis. The Children's Oncology Group completed a Phase II study using oral etoposide …

Sophoridine is an alkaloid extracted from Sophora alopecuroides that has extensive
pharmacological actions. In the present study, the effect of sophoridine on cell growth of …

Medulloblastoma is a highly malignant brain tumor that predominately affects children and
requires multimodal treatment, including chemotherapy with alkylating agents. O6 …

Neurocognitive disorders are a common long-term effect in brain tumor survivors. The rate of
intelligence quotient (IQ) decline is associated with a several risk factors, including tumor …

Adult medulloblastoma is a rare disease accounting for only 1% of adult primary central
nervous system neoplasms. Dramatic advances have been made in the understanding of …