[HTML][HTML] Pathogenesis of deep endometriosis

S Gordts, P Koninckx, I Brosens - Fertility and sterility, 2017 - Elsevier
The pathophysiology of (deep) endometriosis is still unclear. As originally suggested by
Cullen, change the definition “deeper than 5 mm” to “adenomyosis externa.” With the …

Recent insights on the genetics and epigenetics of endometriosis

B Borghese, KT Zondervan, MS Abrao… - Clinical …, 2017 - Wiley Online Library
Endometriosis is a gynecologic disease affecting up to 10% of the women and a major
cause of pain and infertility. It is characterized by the implantation of functional endometrial …

Meta-analysis identifies five novel loci associated with endometriosis highlighting key genes involved in hormone metabolism

Y Sapkota, V Steinthorsdottir, AP Morris… - Nature …, 2017 - nature.com
Endometriosis is a heritable hormone-dependent gynecological disorder, associated with
severe pelvic pain and reduced fertility; however, its molecular mechanisms remain largely …

Genome-wide genetic analyses highlight mitogen-activated protein kinase (MAPK) signaling in the pathogenesis of endometriosis

O Uimari, N Rahmioglu, DR Nyholt… - Human …, 2017 - academic.oup.com
STUDY QUESTION Do genome-wide association study (GWAS) data for endometriosis
provide insight into novel biological pathways associated with its pathogenesis? SUMMARY …

Pathophysiology and management of urinary tract endometriosis

C Nezhat, R Falik, S McKinney, LP King - Nature Reviews Urology, 2017 - nature.com
Endometriosis predominantly affects the pelvic reproductive organs but can also affect the
urinary tract. A number of theories for the pathogenesis of endometriosis have been …

[HTML][HTML] The role of gene polymorphisms in endometriosis

M Matalliotakis, MI Zervou… - Molecular …, 2017 - spandidos-publications.com
Endometriosis is a benign gynecologic disorder, affecting up to 10% of women,
characterized by the presence of functional endometrial tissue at ectopic positions generally …

Reproductive and lifestyle factors associated with endometriosis in a large cross-sectional population sample

R Saha, R Kuja-Halkola, P Tornvall… - Journal of women's …, 2017 - liebertpub.com
Objectives: Despite the high prevalence of endometriosis among women of reproductive
age, risk factors or markers for developing the condition remain largely unknown. Many of …

[HTML][HTML] Validity of self-reported endometriosis and endometriosis-related questions in a Swedish female twin cohort

R Saha, L Marions, P Tornvall - Fertility and sterility, 2017 - Elsevier
Objective To examine the validity of self-reported endometriosis and to improve the reliability
of questionnaires by including endometriosis-related questions. Design Analysis of survey …

[HTML][HTML] Diagnostic and treatment guidelines for gastrointestinal and genitourinary endometriosis

S Young, MK Burns, L DiFrancesco… - Journal of the Turkish …, 2017 - ncbi.nlm.nih.gov
Endometriosis is commonly misdiagnosed, even among many experienced gynecologists.
Gastrointestinal and genitourinary endometriosis is particularly difficult to diagnose, and is …

Revisiting the wandering womb: oxytocin in endometriosis and bipolar disorder

NL Dinsdale, BJ Crespi - Hormones and Behavior, 2017 - Elsevier
Hippocrates attributed women's high emotionality–hysteria-to a 'wandering womb'. Although
hysteria diagnoses were abandoned along with the notion that displaced wombs cause …