Why is depression more common among women than among men?

C Kuehner - The Lancet Psychiatry, 2017 - thelancet.com
Women are about twice as likely as are men to develop depression during their lifetime. This
Series paper summarises evidence regarding the epidemiology on gender differences in …

Choosing prediction over explanation in psychology: Lessons from machine learning

T Yarkoni, J Westfall - Perspectives on Psychological …, 2017 - journals.sagepub.com
Psychology has historically been concerned, first and foremost, with explaining the causal
mechanisms that give rise to behavior. Randomized, tightly controlled experiments are …

Integrating personality structure, personality process, and personality development

A Baumert, M Schmitt, M Perugini… - European Journal …, 2017 - journals.sagepub.com
In this target article, we argue that personality processes, personality structure, and
personality development have to be understood and investigated in integrated ways in order …

Genome-wide analyses for personality traits identify six genomic loci and show correlations with psychiatric disorders

MT Lo, DA Hinds, JY Tung, C Franz, CC Fan, Y Wang… - Nature …, 2017 - nature.com
Personality is influenced by genetic and environmental factors and associated with mental
health. However, the underlying genetic determinants are largely unknown. We identified six …

Genetics of generalized anxiety disorder and related traits

MG Gottschalk, K Domschke - Dialogues in clinical neuroscience, 2017 - Taylor & Francis
This review serves as a systematic guide to the genetics of generalized anxiety disorder
(GAD) and further focuses on anxiety-relevant endophenotypes, such as pathological worry …

[HTML][HTML] Heterogeneity in polygenic scores for common human traits

EB Ware, LL Schmitz, J Faul, A Gard, C Mitchell… - BioRxiv, 2017 - biorxiv.org
This study investigates the creation of polygenic scores (PGS) s for human population
research. PGSs are a linear, usually weighted, combination of risk alleles that estimate the …

Adverse metabolic and mental health outcomes associated with shiftwork in a population-based study of 277,168 workers in UK biobank

CA Wyse, CA Celis Morales, N Graham, Y Fan… - Annals of …, 2017 - Taylor & Francis
Background: Reported associations between shiftwork and health have largely been based
on occupation-specific, or single sex studies that might not be generalizable to the entire …

Genetic risk variants for social anxiety

MB Stein, CY Chen, S Jain, KP Jensen… - American Journal of …, 2017 - Wiley Online Library
Social anxiety is a neurobehavioral trait characterized by fear and reticence in social
situations. Twin studies have shown that social anxiety has a heritable basis, shared with …

[HTML][HTML] Genome-wide analysis in UK Biobank identifies four loci associated with mood instability and genetic correlation with major depressive disorder, anxiety …

J Ward, RJ Strawbridge, MES Bailey, N Graham… - Translational …, 2017 - nature.com
Mood instability is a core clinical feature of affective and psychotic disorders. In keeping with
the Research Domain Criteria approach, it may be a useful construct for identifying biology …

[HTML][HTML] Hair cortisol in twins: Heritability and genetic overlap with psychological variables and stress-system genes

L Rietschel, F Streit, G Zhu, K McAloney, J Frank… - Scientific reports, 2017 - nature.com
Hair cortisol concentration (HCC) is a promising measure of long-term hypothalamus-
pituitary-adrenal (HPA) axis activity. Previous research has suggested an association …