[HTML][HTML] Dendritic cells based immunotherapy

N Shang, M Figini, J Shangguan, B Wang… - American journal of …, 2017 - ncbi.nlm.nih.gov
Dendritic cells (DCs) are the most potent antigen-presenting cells, and tumor antigen-loaded
DCs (DC-vaccines) can activate tumor-specific cytotoxic T lymphocytes (CTLs) in lymphatic …

Terminally modified RNA

T Chakraborty, S Bancel, SG Hoge, A Roy… - US Patent …, 2017 - Google Patents
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Delivery and formulation of engineered nucleic acids

A De Fougerolles, SM Elbashir - US Patent 9,533,047, 2017 - Google Patents
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Engineered nucleic acids and methods of use thereof

JP Schrum, GJ Sieczkiewicz, K Ejebe… - US Patent …, 2017 - Google Patents
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Modified polynucleotides encoding hepatitis A virus cellular receptor 2

S Bancel, T Chakraborty, A De Fougerolles… - US Patent …, 2017 - Google Patents
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Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins

S Bancel, T Chakraborty, A De Fougerolles… - US Patent …, 2017 - Google Patents
2016-05-02 Assigned to MODERNA THERAPEUTICS, INC. reassignment MODERNA
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[HTML][HTML] The basics of artificial antigen presenting cells in T cell-based cancer immunotherapies

LR Neal, SR Bailey, MM Wyatt, JS Bowers… - … research and therapy, 2017 - ncbi.nlm.nih.gov
Adoptive T cell transfer (ACT) can mediate objective responses in patients with advanced
malignancies. There have been major advances in this field, including the optimization of …

Modified polynucleotides for the production of oncology-related proteins and peptides

S Bancel, T Chakraborty, A De Fougerolles… - US Patent …, 2017 - Google Patents
2016-03-17 Assigned to MODERNA THERAPEUTICS, INC. reassignment MODERNA
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Accessory molecule and costimulation requirements for CD4 T cell response

M Croft, C Dubey - Critical Reviews™ in Immunology, 2017 - dl.begellhouse.com
ABSTRACT T cell activation is brought about by recognition of peptide/MHC complexes on
an antigen-presenting cell (APC) by the T cell receptor (TCR). However, in general this …

Modified nucleosides, nucleotides, and nucleic acids, and uses thereof

JP Schrum, S Siddiqi, K Ejebe - US Patent 9,657,295, 2017 - Google Patents
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